A predictive timeline of wildlife population collapse
Contemporary rates of biodiversity decline emphasize the need for reliable ecological
forecasting, but current methods vary in their ability to predict the declines of real-world …
forecasting, but current methods vary in their ability to predict the declines of real-world …
The hyperfunction theory: an emerging paradigm for the biology of aging
The process of senescence (aging) is predominantly determined by the action of wild-type
genes. For most organisms, this does not reflect any adaptive function that senescence …
genes. For most organisms, this does not reflect any adaptive function that senescence …
CD38 dictates age-related NAD decline and mitochondrial dysfunction through an SIRT3-dependent mechanism
Nicotinamide adenine dinucleotide (NAD) levels decrease during aging and are involved in
age-related metabolic decline. To date, the mechanism responsible for the age-related …
age-related metabolic decline. To date, the mechanism responsible for the age-related …
Trade-offs (and constraints) in organismal biology
Trade-offs and constraints are inherent to life, and studies of these phenomena play a
central role in both organismal and evolutionary biology. Trade-offs can be defined …
central role in both organismal and evolutionary biology. Trade-offs can be defined …
The behavioural constellation of deprivation: Causes and consequences
Socioeconomic differences in behaviour are pervasive and well documented, but their
causes are not yet well understood. Here, we make the case that a cluster of behaviours is …
causes are not yet well understood. Here, we make the case that a cluster of behaviours is …
Senescence in natural populations of animals: widespread evidence and its implications for bio-gerontology
That senescence is rarely, if ever, observed in natural populations is an oft-quoted fallacy
within bio-gerontology. We identify the roots of this fallacy in the otherwise seminal works of …
within bio-gerontology. We identify the roots of this fallacy in the otherwise seminal works of …
Early-late life trade-offs and the evolution of ageing in the wild
Empirical evidence for declines in fitness components (survival and reproductive
performance) with age has recently accumulated in wild populations, highlighting that the …
performance) with age has recently accumulated in wild populations, highlighting that the …
[HTML][HTML] The free radical theory of aging matures
Abstract Beckman, Kenneth B., and Bruce N. Ames. The Free Radical Theory of Aging
Matures. Physiol. Rev. 78: 547–581, 1998.—The free radical theory of aging, conceived in …
Matures. Physiol. Rev. 78: 547–581, 1998.—The free radical theory of aging, conceived in …
Understanding the odd science of aging
Evolutionary considerations suggest aging is caused not by active gene programming but by
evolved limitations in somatic maintenance, resulting in a build-up of damage. Ecological …
evolved limitations in somatic maintenance, resulting in a build-up of damage. Ecological …
Life history theory and evolutionary psychology
This chapter provides an overview of life history theory (LHT). LHT conceptualizes specific
allocation tradeoffs in terms of three broad, fundamental trade‐offs: the present‐future …
allocation tradeoffs in terms of three broad, fundamental trade‐offs: the present‐future …