Cancers make their own luck: theories of cancer origins

A Jassim, EP Rahrmann, BD Simons… - Nature reviews …, 2023 - nature.com
Cancer has been a leading cause of death for decades. This dismal statistic has increased
efforts to prevent the disease or to detect it early, when treatment is less invasive, relatively …

High-risk oncogenic human cytomegalovirus

G Herbein - Viruses, 2022 - mdpi.com
Human cytomegalovirus (HCMV) is a herpesvirus that infects between 40% and 95% of the
population worldwide, usually without symptoms. The host immune response keeps the …

[HTML][HTML] Regulation of the aryl hydrocarbon receptor in cancer and cancer stem cells of gynecological malignancies: An update on signaling pathways

L Therachiyil, OJ Hussein, S Uddin… - Seminars in Cancer …, 2022 - Elsevier
Gynecological malignancies are a female type of cancers that affects the reproductive
system. Cancer metastasis or recurrence mediated by cellular invasiveness occurs at …

Epigenetic and genetic keys to fight hpv-related cancers

V Folliero, F Dell'Annunziata, A Chianese, MV Morone… - Cancers, 2023 - mdpi.com
Simple Summary Human papillomavirus (HPV) infection is a highly prevalent sexually
transmitted disease globally. Although most HPV infections do not result in cancer, certain …

[HTML][HTML] The origin of Human Papillomavirus (HPV)—Induced cervical squamous cancer

S Regauer, O Reich - Current opinion in virology, 2021 - Elsevier
Highlights•The vulnerable area or epithelial site at risk for HPV-induced squamous cervical
cancer is prenatally determined.•The area at risk for squamous cervical cancer is defined by …

Is the physiological composition of the vaginal microbiome altered in high-risk HPV infection of the uterine cervix?

T Rokos, V Holubekova, Z Kolkova, A Hornakova… - Viruses, 2022 - mdpi.com
Background: Cervical cancer is the fourth most common malignancy and fourth leading
cause of cancer death in women worldwide. More than 99.7% of cases are caused by …

N6-methyladenosine modification of CENPK mRNA by ZC3H13 promotes cervical cancer stemness and chemoresistance

X Lin, F Wang, J Chen, J Liu, YB Lin, L Li… - Military Medical …, 2022 - Springer
Background Stemness and chemoresistance contribute to cervical cancer recurrence and
metastasis. In the current study, we determined the relevant players and role of N 6 …

Immune-inhibitory gene expression is positively correlated with overall immune activity and predicts increased survival probability of cervical and head and neck …

M Budhwani, G Turrell, M Yu, IH Frazer… - Frontiers in Molecular …, 2021 - frontiersin.org
Background: Limited immunotherapy options are approved for the treatment of cervical
cancer and only 10–25% of patients respond effectively to checkpoint inhibition …

Nanotechnology based vaccines: Cervical cancer management and perspectives

R Jasrotia, DS Dhanjal, S Bhardwaj, P Sharma… - Journal of Drug Delivery …, 2022 - Elsevier
In spite of being highly preventable through screening strategies and early vaccination,
cervical cancer has become the utmost common type of gynaecological malignancy globally …

Differential association of hedgehog pathway in development of cervical carcinoma and its chemo-tolerance

D Pal, S Samadder, P Dutta, A Roychowdhury… - … -Research and Practice, 2023 - Elsevier
Cervical carcinoma (CACX) is still a dreadful threat to women in develo** countries.
Available conventional chemo-radiation therapies are not sufficient to restrict the disease …