The outbreak of 2019-novel coronavirus disease (COVID-19), caused by SARS-CoV-2,
started in late 2019; in a short time, it has spread rapidly all over the world. Although some …

Metagenomic next-generation sequencing (mNGS) is increasingly being applied in clinical
laboratories for unbiased culture-independent diagnosis. Whether it can be a next routine …

The application of sequencing technology is shifting from research to clinical laboratories
owing to rapid technological developments and substantially reduced costs. However …

Lower respiratory tract infections are associated with high morbidity and mortality and
significant clinical harm. Due to the limited ability of traditional pathogen detection methods …

Objective We aim to familiarize the application status of metagenomic sequencing in
diagnosing pulmonary infections, to compare metagenomic sequencing with traditional …

Background More than 2 months separated the initial description of SARS-CoV-2 and
discovery of its widespread dissemination in the United States. Despite this lengthy interval …

Metagenomic next-generation sequencing (mNGS) is a transformative approach in the
diagnosis of infectious diseases, utilizing unbiased high-throughput sequencing to directly …

Human bocaviruses were first described between 2005 and 2010, identified in respiratory
and enteric tract samples of children. Screening studies have shown worldwide distribution …

Using metagenomics analysis, we are the first to identify the presence of a small, circular,
single-stranded Gemykibivirus (GkV) genome from the respiratory tract of an elderly woman …

The common cold is the primary cause of illness in the community, with over 200 viral strains
identified, and rhinovirus infections being the most prevalent. Coronavirus Disease 19 …