NOD-like receptor-mediated plant immunity: from structure to cell death

IML Saur, R Panstruga, P Schulze-Lefert - Nature Reviews Immunology, 2021 - nature.com
Animal and plant immune systems use intracellular nucleotide-binding oligomerization
domain (NOD)-like receptors (NLRs) to detect pathogens, resulting in the activation of …

Effector-triggered immunity: from pathogen perception to robust defense

H Cui, K Tsuda, JE Parker - Annual review of plant biology, 2015 - annualreviews.org
In plant innate immunity, individual cells have the capacity to sense and respond to
pathogen attack. Intracellular recognition mechanisms have evolved to intercept …

Direct pathogen-induced assembly of an NLR immune receptor complex to form a holoenzyme

S Ma, D Lapin, LI Liu, Y Sun, W Song, X Zhang… - Science, 2020 - science.org
INTRODUCTION Discrimination of self from nonself is pivotal for cellular organisms, as it
allows the perception of pathogenic invaders that might otherwise multiply unchecked and …

Pathogen effector AvrSr35 triggers Sr35 resistosome assembly via a direct recognition mechanism

YB Zhao, MX Liu, TT Chen, X Ma, ZK Li, Z Zheng… - Science …, 2022 - science.org
Nucleotide-binding, leucine-rich repeat receptors (NLRs) perceive pathogen effectors to
trigger plant immunity. The direct recognition mechanism of pathogen effectors by coiled-coil …

Reconstitution and structure of a plant NLR resistosome conferring immunity

J Wang, M Hu, J Wang, J Qi, Z Han, G Wang, Y Qi… - Science, 2019 - science.org
INTRODUCTION Nucleotide-binding (NB), leucine-rich repeat (LRR) receptors (NLRs)
mediate plant immunity by directly or indirectly sensing pathogen effector proteins delivered …

Epigenetic regulation of antagonistic receptors confers rice blast resistance with yield balance

Y Deng, K Zhai, Z **e, D Yang, X Zhu, J Liu, X Wang… - Science, 2017 - science.org
Crop breeding aims to balance disease resistance with yield; however, single resistance (R)
genes can lead to resistance breakdown, and R gene pyramiding may affect growth fitness …

Effector‐dependent activation and oligomerization of plant NRC class helper NLRs by sensor NLR immune receptors Rpi‐amr3 and Rpi‐amr1

HK Ahn, X Lin, AC Olave‐Achury, L Derevnina… - The EMBO …, 2023 - embopress.org
Plant pathogens compromise crop yields. Plants have evolved robust innate immunity that
depends in part on intracellular Nucleotide‐binding, Leucine rich‐Repeat (NLR) immune …

Diverse NLR immune receptors activate defence via the RPW 8‐NLR NRG 1

B Castel, PM Ngou, V Cevik, A Redkar, DS Kim… - New …, 2019 - Wiley Online Library
Most land plant genomes carry genes that encode RPW 8‐NLR Resistance (R) proteins.
Angiosperms carry two RPW 8‐NLR subclasses: ADR 1 and NRG 1. ADR 1s act as …

Structure, biochemical function, and signaling mechanism of plant NLRs

J Wang, W Song, J Chai - Molecular Plant, 2023 - cell.com
To counter pathogen invasion, plants have evolved a large number of immune receptors,
including membrane-resident pattern recognition receptors (PRRs) and intracellular …

NLR singletons, pairs, and networks: evolution, assembly, and regulation of the intracellular immunoreceptor circuitry of plants

H Adachi, L Derevnina, S Kamoun - Current opinion in plant biology, 2019 - Elsevier
Highlights•NLRs may have evolved from singletons to pairs and networks.•Assembly of
immunoreceptor complexes is associated with NLR activation.•NLR (mis) regulation …