The origin and evolution of Wnt signalling

M Holzem, M Boutros, TW Holstein - Nature Reviews Genetics, 2024 - nature.com
The Wnt signal transduction pathway has essential roles in the formation of the primary body
axis during development, cellular differentiation and tissue homeostasis. This animal …

Evolution by gene loss

R Albalat, C Cañestro - Nature Reviews Genetics, 2016 - nature.com
The recent increase in genomic data is revealing an unexpected perspective of gene loss as
a pervasive source of genetic variation that can cause adaptive phenotypic diversity. This …

Ancient gene linkages support ctenophores as sister to other animals

DT Schultz, SHD Haddock, JV Bredeson, RE Green… - Nature, 2023 - nature.com
A central question in evolutionary biology is whether sponges or ctenophores (comb jellies)
are the sister group to all other animals. These alternative phylogenetic hypotheses imply …

BRAKER2: automatic eukaryotic genome annotation with GeneMark-EP+ and AUGUSTUS supported by a protein database

T Brůna, KJ Hoff, A Lomsadze, M Stanke… - NAR genomics and …, 2021 - academic.oup.com
The task of eukaryotic genome annotation remains challenging. Only a few genomes could
serve as standards of annotation achieved through a tremendous investment of human …

Deeply conserved synteny and the evolution of metazoan chromosomes

O Simakov, J Bredeson, K Berkoff, F Marletaz… - Science …, 2022 - science.org
Animal genomes show networks of deeply conserved gene linkages whose phylogenetic
scope and chromosomal context remain unclear. Here, we report chromosome-scale …

[HTML][HTML] Divergent genomic trajectories predate the origin of animals and fungi

E Ocaña-Pallarès, TA Williams, D López-Escardó… - Nature, 2022 - nature.com
Animals and fungi have radically distinct morphologies, yet both evolved within the same
eukaryotic supergroup: Opisthokonta,. Here we reconstructed the trajectory of genetic …

A phylum-level phylogenetic classification of zygomycete fungi based on genome-scale data

JW Spatafora, Y Chang, GL Benny, K Lazarus… - Mycologia, 2016 - Taylor & Francis
Zygomycete fungi were classified as a single phylum, Zygomycota, based on sexual
reproduction by zygospores, frequent asexual reproduction by sporangia, absence of …

The origin of animal multicellularity and cell differentiation

T Brunet, N King - Developmental cell, 2017 - cell.com
Over 600 million years ago, animals evolved from a unicellular or colonial organism whose
cell (s) captured bacteria with a collar complex, a flagellum surrounded by a microvillar …

The origin of Metazoa: a unicellular perspective

A Sebé-Pedrós, BM Degnan, I Ruiz-Trillo - Nature Reviews Genetics, 2017 - nature.com
The first animals evolved from an unknown single-celled ancestor in the Precambrian
period. Recently, the identification and characterization of the genomic and cellular traits of …

The origin of animals: an ancestral reconstruction of the unicellular-to-multicellular transition

N Ros-Rocher, A Pérez-Posada, MM Leger… - Open …, 2021 - royalsocietypublishing.org
How animals evolved from a single-celled ancestor, transitioning from a unicellular lifestyle
to a coordinated multicellular entity, remains a fascinating question. Key events in this …