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The origin and evolution of Wnt signalling
The Wnt signal transduction pathway has essential roles in the formation of the primary body
axis during development, cellular differentiation and tissue homeostasis. This animal …
axis during development, cellular differentiation and tissue homeostasis. This animal …
Evolution by gene loss
The recent increase in genomic data is revealing an unexpected perspective of gene loss as
a pervasive source of genetic variation that can cause adaptive phenotypic diversity. This …
a pervasive source of genetic variation that can cause adaptive phenotypic diversity. This …
Ancient gene linkages support ctenophores as sister to other animals
A central question in evolutionary biology is whether sponges or ctenophores (comb jellies)
are the sister group to all other animals. These alternative phylogenetic hypotheses imply …
are the sister group to all other animals. These alternative phylogenetic hypotheses imply …
BRAKER2: automatic eukaryotic genome annotation with GeneMark-EP+ and AUGUSTUS supported by a protein database
The task of eukaryotic genome annotation remains challenging. Only a few genomes could
serve as standards of annotation achieved through a tremendous investment of human …
serve as standards of annotation achieved through a tremendous investment of human …
Deeply conserved synteny and the evolution of metazoan chromosomes
Animal genomes show networks of deeply conserved gene linkages whose phylogenetic
scope and chromosomal context remain unclear. Here, we report chromosome-scale …
scope and chromosomal context remain unclear. Here, we report chromosome-scale …
[HTML][HTML] Divergent genomic trajectories predate the origin of animals and fungi
Animals and fungi have radically distinct morphologies, yet both evolved within the same
eukaryotic supergroup: Opisthokonta,. Here we reconstructed the trajectory of genetic …
eukaryotic supergroup: Opisthokonta,. Here we reconstructed the trajectory of genetic …
A phylum-level phylogenetic classification of zygomycete fungi based on genome-scale data
Zygomycete fungi were classified as a single phylum, Zygomycota, based on sexual
reproduction by zygospores, frequent asexual reproduction by sporangia, absence of …
reproduction by zygospores, frequent asexual reproduction by sporangia, absence of …
The origin of animal multicellularity and cell differentiation
Over 600 million years ago, animals evolved from a unicellular or colonial organism whose
cell (s) captured bacteria with a collar complex, a flagellum surrounded by a microvillar …
cell (s) captured bacteria with a collar complex, a flagellum surrounded by a microvillar …
The origin of Metazoa: a unicellular perspective
The first animals evolved from an unknown single-celled ancestor in the Precambrian
period. Recently, the identification and characterization of the genomic and cellular traits of …
period. Recently, the identification and characterization of the genomic and cellular traits of …
The origin of animals: an ancestral reconstruction of the unicellular-to-multicellular transition
How animals evolved from a single-celled ancestor, transitioning from a unicellular lifestyle
to a coordinated multicellular entity, remains a fascinating question. Key events in this …
to a coordinated multicellular entity, remains a fascinating question. Key events in this …