The stepped wedge cluster randomized design has received increasing attention in
pragmatic clinical trials and implementation science research. The key feature of the design …

Praise for the Second Edition" A must-have book for anyone expecting to do research and/or
applications in categorical data analysis."—Statistics in Medicine" It is a total delight reading …

Background Thrombolytic therapy for acute ischemic stroke has been approached
cautiously because there were high rates of intracerebral hemorrhage in early clinical trials …

A milestone in the published literature on the subject, this first-ever Handbook of Beta
Distribution and Its Applications clearly enumerates the properties of beta distributions and …

Background The frequency of major malformations, growth retardation, and hypoplasia of
the midface and fingers, known as anticonvulsant embryopathy, is increased in infants …

Clustered data are found in many different types of studies, for example, studies involving
repeated measures, inter‐rater agreement studies, household surveys, crossover designs …

Objective To determine medical students' perceptions of having been harassed or belittled
and their correlates, for the purposes of reducing such abuses. Design Longitudinal survey …

This second edition of Models for Repeated Measurements has been comprehensively
revised and updated, taking into account the huge amount of research that has been carried …

We use the concept of a latent variable to derive the joint distribution of a continuous and a
discrete outcome, and then extend the model to allow for clustered data. The model can be …

Background The National Institute of Neurological Disorders and Stroke (NINDS) held a
workshop on statistical approaches to analysis of acute stroke trials that have multiple …