Modeling polymorphic molecular crystals with electronic structure theory

GJO Beran - Chemical reviews, 2016 - ACS Publications
Interest in molecular crystals has grown thanks to their relevance to pharmaceuticals,
organic semiconductor materials, foods, and many other applications. Electronic structure …

Quantum chemistry calculations for metabolomics: Focus review

RM Borges, SM Colby, S Das, AS Edison… - Chemical …, 2021 - ACS Publications
A primary goal of metabolomics studies is to fully characterize the small-molecule
composition of complex biological and environmental samples. However, despite advances …

Fully automated quantum‐chemistry‐based computation of spin–spin‐coupled nuclear magnetic resonance spectra

S Grimme, C Bannwarth, S Dohm… - Angewandte Chemie …, 2017 - Wiley Online Library
We present a composite procedure for the quantum‐chemical computation of spin–spin‐
coupled 1H NMR spectra for general, flexible molecules in solution that is based on four …

Extended benchmark set of main-group nuclear shielding constants and NMR chemical shifts and its use to evaluate modern DFT methods

CJ Schattenberg, M Kaupp - Journal of Chemical Theory and …, 2021 - ACS Publications
An extended theoretical benchmark set, NS372, for light main-group nuclear shieldings and
NMR shifts has been constructed based on high-level GIAO-CCSD (T)/pcSseg-3//CCSD …

Assessing the accuracy of local hybrid density functional approximations for molecular response properties

C Holzer, YJ Franzke, M Kehry - Journal of Chemical Theory and …, 2021 - ACS Publications
A comprehensive overview of the performance of local hybrid functionals for molecular
properties like excited states, ionization potentials within the GW framework, polarizabilities …

Do double-hybrid exchange–correlation functionals provide accurate chemical shifts? A benchmark assessment for proton NMR

MT de Oliveira, JMA Alves, AAC Braga… - Journal of Chemical …, 2021 - ACS Publications
A benchmark density functional theory (DFT) study of 1H NMR chemical shifts for data sets
comprising 200 chemical shifts, including complex natural products, has been carried out to …

[HTML][HTML] Benchmarking quantum chemical methods: Are we heading in the right direction?

RA Mata, MA Suhm - Angewandte Chemie (International ed. in …, 2017 - ncbi.nlm.nih.gov
Theoreticians and experimentalists should work together more closely to establish reliable
rankings and benchmarks for quantum chemical methods. Comparison to carefully designed …

General Protocol for the Accurate Prediction of Molecular 13C/1H NMR Chemical Shifts via Machine Learning Augmented DFT

P Gao, J Zhang, Q Peng, J Zhang… - Journal of Chemical …, 2020 - ACS Publications
An accurate prediction of NMR chemical shifts at affordable computational cost is very
important for different types of structural assignments in experimental studies. Density …

[HTML][HTML] Exact two-component theory becoming an efficient tool for NMR shieldings and shifts with spin–orbit coupling

YJ Franzke, C Holzer - The Journal of Chemical Physics, 2023 - pubs.aip.org
We present a gauge-origin invariant exact two-component (X2C) approach within a modern
density functional framework, supporting meta-generalized gradient approximations such as …

IMPRESSION–prediction of NMR parameters for 3-dimensional chemical structures using machine learning with near quantum chemical accuracy

W Gerrard, LA Bratholm, MJ Packer, AJ Mulholland… - Chemical …, 2020 - pubs.rsc.org
The IMPRESSION (Intelligent Machine PREdiction of Shift and Scalar information Of Nuclei)
machine learning system provides an efficient and accurate method for the prediction of …