Understanding the role of oxidative stress, neuroinflammation and abnormal myelination in excessive aggression associated with depression: recent input from …

A Gorlova, E Svirin, D Pavlov, R Cespuglio… - International journal of …, 2023 - mdpi.com
Aggression and deficient cognitive control problems are widespread in psychiatric disorders,
including major depressive disorder (MDD). These abnormalities are known to contribute …

From the Friend to the Foe—Enterococcus faecalis Diverse Impact on the Human Immune System

A Daca, T Jarzembowski - International journal of molecular sciences, 2024 - mdpi.com
Enterococcus faecalis is a bacterium which accompanies us from the first days of our life. As
a commensal it produces vitamins, metabolizes nutrients, and maintains intestinal pH. All of …

Myelin and oligodendrocyte lineage cell dysfunctions: New players in the etiology and treatment of depression and stress‐related disorders

E Boda - European Journal of Neuroscience, 2021 - Wiley Online Library
Depressive disorders are complex, multifactorial disorders that have been traditionally
attributed exclusively to neuronal abnormalities. However, recent studies have increased …

Dystrophy of oligodendrocytes and adjacent microglia in prefrontal gray matter in schizophrenia

NA Uranova, OV Vikhreva, VI Rakhmanova… - Frontiers in …, 2020 - frontiersin.org
Background Some evidence support the notion that microglia activation in acute state of
schizophrenia might contribute to damage of oligodendrocytes and myelinated fibers …

Quantitative MRI at 7-Tesla reveals novel frontocortical myeloarchitecture anomalies in major depressive disorder

J Heij, W van der Zwaag, T Knapen, MWA Caan… - Translational …, 2024 - nature.com
Whereas meta-analytical data highlight abnormal frontocortical macrostructure
(thickness/surface area/volume) in Major Depressive Disorder (MDD), the underlying …

Probing brain developmental patterns of myelination and associations with psychopathology in youths using gray/white matter contrast

LB Norbom, NT Doan, D Alnæs, T Kaufmann… - Biological …, 2019 - Elsevier
Background Cerebral myeloarchitecture shows substantial development across childhood
and adolescence, and aberrations in these trajectories are relevant for a range of mental …

[HTML][HTML] Neural markers of familial risk for depression–A systematic review

A Nazarova, M Schmidt, J Cookey, R Uher - Developmental cognitive …, 2022 - Elsevier
Structural and functional brain alterations are found in adults with depression. It is not known
whether these changes are a result of illness or exist prior to disorder onset. Asymptomatic …

Global hypomyelination of the brain white and gray matter in schizophrenia: quantitative imaging using macromolecular proton fraction

LP Smirnova, VL Yarnykh, DA Parshukova… - Translational …, 2021 - nature.com
Myelin deficiency is commonly recognized as an important pathological feature of brain
tissues in schizophrenia (SZ). In this pilot study, global myelin content abnormalities in white …

Depth‐dependent abnormal cortical myelination in first‐episode treatment‐naïve schizophrenia

W Wei, Y Zhang, Y Li, Y Meng, M Li… - Human brain …, 2020 - Wiley Online Library
Myelination is key to effective message passing in the central nervous system and is likely
linked to the pathogenesis of schizophrenia (SZ). Emerging evidence indicates that a large …

Reduced oligodendrocyte density in layer 5 of the prefrontal cortex in schizophrenia

NS Kolomeets, NA Uranova - European archives of psychiatry and clinical …, 2019 - Springer
Neuroimaging and post-mortem studies have implicated altered myelin integrity and
oligodendrocyte abnormalities in the dysfunction of neuronal network in schizophrenia …