Invited review article: current state of research on biological effects of terahertz radiation

GJ Wilmink, JE Grundt - Journal of Infrared, Millimeter, and Terahertz …, 2011 - Springer
Terahertz (THz) imaging and sensing technologies are increasingly being used in a host of
medical, military, and security applications. For example, THz systems are now being tested …

Fluctuations in the DNA double helix: A critical review

MD Frank-Kamenetskii, S Prakash - Physics of life reviews, 2014 - Elsevier
A critical overview of the extensive literature on fluctuations in the DNA double helix is
presented. Both theory and experiment are comprehensively reviewed and analyzed …

DNA breathing dynamics in the presence of a terahertz field

BS Alexandrov, V Gelev, AR Bishop, A Usheva… - Physics Letters A, 2010 - Elsevier
We consider the influence of a terahertz field on the breathing dynamics of double-stranded
DNA. We model the spontaneous formation of spatially localized openings of a damped and …

Mammalian stem cells reprogramming in response to terahertz radiation

J Bock, Y Fukuyo, S Kang, ML Phipps, LB Alexandrov… - PloS one, 2010 - journals.plos.org
We report that extended exposure to broad-spectrum terahertz radiation results in specific
changes in cellular functions that are closely related to DNA-directed gene transcription. Our …

In vitro investigation of the biological effects associated with human dermal fibroblasts exposed to 2.52 THz radiation

GJ Wilmink, BD Rivest, CC Roth, BL Ibey… - Lasers in Surgery …, 2011 - Wiley Online Library
Abstract Background Terahertz (THz) radiation sources are increasingly being used in
military, defense, and medical applications. However, the biological effects associated with …

Physics of base-pairing dynamics in DNA

M Manghi, N Destainville - Physics Reports, 2016 - Elsevier
As a key molecule of life, Deoxyribo-Nucleic Acid (DNA) is the focus of numbers of
investigations with the help of biological, chemical and physical techniques. From a physical …

Prospects for the study of biological systems with high power sources of terahertz radiation

P Weightman - Physical biology, 2012 - iopscience.iop.org
The emergence of intense sources of terahertz radiation based on lasers and electron
accelerators has considerable potential for research on biological systems. This perspective …

Engineering an Acinetobacter regulon for biosensing and high-throughput enzyme screening in E. coli via flow cytometry

RK Jha, TL Kern, DT Fox… - Nucleic acids research, 2014 - academic.oup.com
We created a single cell sorting system to screen for enzyme activity in Escherichia coli
producing 3, 4 dihydroxy benzoate (34DHB). To do so, we engineered a transcription factor …

DNA dynamics play a role as a basal transcription factor in the positioning and regulation of gene transcription initiation

BS Alexandrov, V Gelev, SW Yoo… - Nucleic acids …, 2010 - academic.oup.com
We assess the role of DNA breathing dynamics as a determinant of promoter strength and
transcription start site (TSS) location. We compare DNA Langevin dynamic profiles of …

A nonlinear dynamic model of DNA with a sequence-dependent stacking term

BS Alexandrov, V Gelev, Y Monisova… - Nucleic Acids …, 2009 - academic.oup.com
No simple model exists that accurately describes the melting behavior and breathing
dynamics of double-stranded DNA as a function of nucleotide sequence. This is especially …