Isatins as privileged molecules in design and synthesis of spiro-fused cyclic frameworks

GS Singh, ZY Desta - Chemical Reviews, 2012 - ACS Publications
1. INTRODUCTION Indoline-2, 3-dione or indole-1H-2, 3-dione (Figure 1), commonly known
as isatin, is a well-known natural product found in plants of genus Isatis and in Couropita …

Recent contributions from the Baylis− Hillman reaction to organic chemistry

D Basavaiah, BS Reddy, SS Badsara - Chemical reviews, 2010 - ACS Publications
Organic synthesis is one of the most successful and useful disciplines of science and mainly
involves the construction of carbon-carbon bond (s) and carbon-heteroatom bond (s) and …

Recent progress in synthesis and bioactivity studies of indolizines

GS Singh, EE Mmatli - European journal of medicinal chemistry, 2011 - Elsevier
The present review describes the recent progress in synthetic approaches to construct
indolizine framework (including partially or wholly reduced ring) and the design of such …

The Baylis–Hillman reaction: a novel source of attraction, opportunities, and challenges in synthetic chemistry

D Basavaiah, KV Rao, RJ Reddy - Chemical Society Reviews, 2007 - pubs.rsc.org
The Baylis–Hillman reaction is a successful, useful, and atom-economical carbon–carbon
bond forming reaction, which has grown from an obscure level to the level of high synthetic …

Advances in the Baylis–Hillman reaction-assisted synthesis of cyclic frameworks

V Singh, S Batra - Tetrahedron, 2008 - Elsevier
Acquiring the capability to access structurally complex and diverse molecules through
simple starting substrates has been one of the underlying principles of chemical research …

Electrochemical direct C–H mono and bis-chalcogenation of indolizine frameworks under oxidant-free conditions

A Chouhan, K Ucheniya, L Yadav, PK Jat… - Organic & …, 2023 - pubs.rsc.org
Herein, we disclosed a sustainable electrochemical approach for site-selective C–H mono
and bis-chalcogenation (sulfenylation or selenylation) of indolizine frameworks. Diversely …

The Baylis–Hillman reaction: a new continent in organic chemistry–our philosophy, vision and over three decades of research

D Basavaiah, RT Naganaboina - New Journal of Chemistry, 2018 - pubs.rsc.org
This review describes, in brief, the philosophy, vision and long-term research experience of
the senior author (DB) in the area of the Baylis–Hillman (BH)[also known as the Morita …

One-pot organocatalyzed synthesis of tricyclic indolizines

LA Zeoly, LV Acconcia, MT Rodrigues… - Organic & …, 2023 - pubs.rsc.org
Indolizines and their saturated derivatives are important structural motifs present in several
biologically active compounds of both natural and synthetic origin. We describe herein a one …

Simple and One-Pot Protocol for Synthesis of Indene-spiro-oxindoles Involving Tandem Prins and Friedel− Crafts Reactions

D Basavaiah, KR Reddy - Organic Letters, 2007 - ACS Publications
A simple and one-pot protocol for the synthesis of indene-spiro-oxindole derivatives via
TiCl4-mediated reaction between 1, 1-diarylethylenes and isatin derivatives involving …

Iodine-Mediated Domino Cyclization for One-Pot Synthesis of Indolizine-Fused Chromones via Metal-Free sp3 C–H Functionalization

XJ Zhang, Z Wang, H Zhang, JJ Gao… - The Journal of …, 2021 - ACS Publications
An efficient method for the synthesis of new indolizine-fused chromones has been
accomplished from ethyl (E)-3-(2-acetylphenoxy) acrylates and pyridines in a “one-pot” …