Protein reconstitution inside giant unilamellar vesicles
T Litschel, P Schwille - Annual Review of Biophysics, 2021 - annualreviews.org
Giant unilamellar vesicles (GUVs) have gained great popularity as mimicries for cellular
membranes. As their sizes are comfortably above the optical resolution limit, and their lipid …
membranes. As their sizes are comfortably above the optical resolution limit, and their lipid …
Actin cytoskeleton dynamics in mammalian oocyte meiosis
X Duan, SC Sun - Biology of Reproduction, 2019 - academic.oup.com
During mitosis, cells undergo symmetrical cell division, while oocyte meiotic maturation
undergoes two consecutive, asymmetric divisions that generate a totipotent haploid oocyte …
undergoes two consecutive, asymmetric divisions that generate a totipotent haploid oocyte …
Reconstitution of contractile actomyosin rings in vesicles
T Litschel, CF Kelley, D Holz, M Adeli Koudehi… - Nature …, 2021 - nature.com
One of the grand challenges of bottom-up synthetic biology is the development of minimal
machineries for cell division. The mechanical transformation of large-scale compartments …
machineries for cell division. The mechanical transformation of large-scale compartments …
F-actin architecture determines constraints on myosin thick filament motion
Active stresses are generated and transmitted throughout diverse F-actin architectures
within the cell cytoskeleton, and drive essential behaviors of the cell, from cell division to …
within the cell cytoskeleton, and drive essential behaviors of the cell, from cell division to …
The 2018 biomembrane curvature and remodeling roadmap
P Bassereau, R **, T Baumgart… - Journal of physics D …, 2018 - iopscience.iop.org
The importance of curvature as a structural feature of biological membranes has been
recognized for many years and has fascinated scientists from a wide range of different …
recognized for many years and has fascinated scientists from a wide range of different …
Architecture and connectivity govern actin network contractility
Actomyosin contractility plays a central role in a wide range of cellular processes, including
the establishment of cell polarity, cell migration, tissue integrity, and morphogenesis during …
the establishment of cell polarity, cell migration, tissue integrity, and morphogenesis during …
Confinement sensing and signal optimization via Piezo1/PKA and myosin II pathways
Cells adopt distinct signaling pathways to optimize cell locomotion in different physical
microenvironments. However, the underlying mechanism that enables cells to sense and …
microenvironments. However, the underlying mechanism that enables cells to sense and …
Encapsulation of the cytoskeleton: towards mimicking the mechanics of a cell
Y Bashirzadeh, AP Liu - Soft Matter, 2019 - pubs.rsc.org
The cytoskeleton of a cell controls all the aspects of cell shape changes and motility from its
physiological functions for survival to reproduction to death. The structure and dynamics of …
physiological functions for survival to reproduction to death. The structure and dynamics of …
Actin dynamics drive cell-like membrane deformation
Cell membrane deformations are crucial for proper cell function. Specialized protein
assemblies initiate inward or outward membrane deformations that the cell uses respectively …
assemblies initiate inward or outward membrane deformations that the cell uses respectively …
Cytoskeletal tension actively sustains the migratory T‐cell synaptic contact
When migratory T cells encounter antigen‐presenting cells (APCs), they arrest and form
radially symmetric, stable intercellular junctions termed immunological synapses which …
radially symmetric, stable intercellular junctions termed immunological synapses which …