Immunology of Mycobacterium tuberculosis Infections
Tuberculosis (TB) is a serious global public health challenge that results in significant
morbidity and mortality worldwide. TB is caused by infection with the bacilli Mycobacterium …
morbidity and mortality worldwide. TB is caused by infection with the bacilli Mycobacterium …
Tuberculosis phenotypic and genotypic drug susceptibility testing and immunodiagnostics: a review
KA Yusoof, JI García, A Schami… - Frontiers in …, 2022 - frontiersin.org
Tuberculosis (TB), considered an ancient disease, is still killing one person every 21
seconds. Diagnosis of Mycobacterium tuberculosis (M. tb) still has many challenges …
seconds. Diagnosis of Mycobacterium tuberculosis (M. tb) still has many challenges …
[HTML][HTML] Relationship of SARS-CoV-2–specific CD4 response to COVID-19 severity and impact of HIV-1 and tuberculosis coinfection
JCI - Relationship of SARS-CoV-2–specific CD4 response to COVID-19 severity and impact of
HIV-1 and tuberculosis coinfection Go to JCI Insight About Editors Consulting Editors For authors …
HIV-1 and tuberculosis coinfection Go to JCI Insight About Editors Consulting Editors For authors …
[HTML][HTML] Diagnosis and biomarkers for ocular tuberculosis: From the present into the future
Tuberculosis is an airborne disease caused by Mycobacterium tuberculosis (Mtb) and can
manifest both pulmonary and extrapulmonary disease, including ocular tuberculosis (OTB) …
manifest both pulmonary and extrapulmonary disease, including ocular tuberculosis (OTB) …
HLA-DR marks recently divided antigen-specific effector CD4 T cells in active tuberculosis patients
Upon Ag encounter, T cells can rapidly divide and form an effector population, which plays
an important role in fighting acute infections. In humans, little is known about the molecular …
an important role in fighting acute infections. In humans, little is known about the molecular …
Classical CD4 T cells as the cornerstone of antimycobacterial immunity
J Morgan, K Muskat, R Tippalagama… - Immunological …, 2021 - Wiley Online Library
Tuberculosis is a significant health problem without an effective vaccine to combat it. A
thorough understanding of the immune response and correlates of protection is needed to …
thorough understanding of the immune response and correlates of protection is needed to …
Antigen-specific T-cell activation distinguishes between recent and remote tuberculosis infection
Rationale: Current diagnostic tests fail to identify individuals at higher risk of progression to
tuberculosis disease, such as those with recent Mycobacterium tuberculosis infection, who …
tuberculosis disease, such as those with recent Mycobacterium tuberculosis infection, who …
Disease extent and anti‐tubercular treatment response correlates with Mycobacterium tuberculosis‐specific CD4 T‐cell phenotype regardless of HIV‐1 status
Objectives The development of non‐sputum‐based assays for tuberculosis (TB) diagnosis
and treatment monitoring is a key priority. Recent data indicate that whole blood‐based …
and treatment monitoring is a key priority. Recent data indicate that whole blood‐based …
Host resistance to pulmonary Mycobacterium tuberculosis infection requires CD153 expression
MA Sallin, KD Kauffman, C Riou, E Du Bruyn… - Nature …, 2018 - nature.com
Mycobacterium tuberculosis infection (Mtb) is the leading cause of death due to a single
infectious agent and is among the top ten causes of all human deaths worldwide. CD4 T …
infectious agent and is among the top ten causes of all human deaths worldwide. CD4 T …
Phenotypic changes on Mycobacterium tuberculosis-specific CD4 T cells as surrogate markers for tuberculosis treatment efficacy
Background: The analysis of phenotypic characteristics on Mycobacterium tuberculosis
(MTB)-specific T cells is a promising approach for the diagnosis of active tuberculosis (aTB) …
(MTB)-specific T cells is a promising approach for the diagnosis of active tuberculosis (aTB) …