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Microfluidics for sperm analysis and selection
Infertility is a growing global health issue with far-reaching socioeconomic implications. A
downward trend in male fertility highlights the acute need for affordable and accessible …
downward trend in male fertility highlights the acute need for affordable and accessible …
Machine learning for sperm selection
Infertility rates and the number of couples seeking fertility care have increased worldwide
over the past few decades. Over 2.5 million cycles of assisted reproductive technologies are …
over the past few decades. Over 2.5 million cycles of assisted reproductive technologies are …
Human sperm rheotaxis: a passive physical process
A long-standing question in natural reproduction is how mammalian sperm navigate inside
female reproductive tract and finally reach the egg cell, or oocyte. Recently, fluid flow was …
female reproductive tract and finally reach the egg cell, or oocyte. Recently, fluid flow was …
Curvature in the reproductive tract alters sperm–surface interactions
The fallopian tube is lined with a highly complex folded epithelium surrounding a lumen that
progressively narrows. To study the influence of this labyrinthine complexity on sperm …
progressively narrows. To study the influence of this labyrinthine complexity on sperm …
Rheotaxis-based separation of sperm with progressive motility using a microfluidic corral system
The separation of motile sperm from semen samples is sought after for medical infertility
treatments. In this work, we demonstrate a high-throughput microfluidic device that can …
treatments. In this work, we demonstrate a high-throughput microfluidic device that can …
Advances in sperm analysis: techniques, discoveries and applications
Infertility affects one in six couples worldwide, and fertility continues to deteriorate globally,
partly owing to a decline in semen quality. Sperm analysis has a central role in diagnosing …
partly owing to a decline in semen quality. Sperm analysis has a central role in diagnosing …
Human sperm ion channel (dys) function: implications for fertilization
SG Brown, SJ Publicover, CLR Barratt… - Human reproduction …, 2019 - academic.oup.com
BACKGROUND Intensive research on sperm ion channels has identified members of
several ion channel families in both mouse and human sperm. Gene knock-out studies have …
several ion channel families in both mouse and human sperm. Gene knock-out studies have …
[HTML][HTML] Computer software (SiD) assisted real-time single sperm selection associated with fertilization and blastocyst formation
Research question: Using a novel artificial vision-based software (SiD V1. 0; IVF 2.0, UK),
we aimed to explore a correlation between individual sperm kinematics evaluated in real …
we aimed to explore a correlation between individual sperm kinematics evaluated in real …
Human sperm uses asymmetric and anisotropic flagellar controls to regulate swimming symmetry and cell steering
Flagellar beating drives sperm through the female reproductive tract and is vital for
reproduction. Flagellar waves are generated by thousands of asymmetric molecular …
reproduction. Flagellar waves are generated by thousands of asymmetric molecular …
Live births from artificial insemination of microfluidic-sorted bovine spermatozoa characterized by trajectories correlated with fertility
MPB Nagata, K Endo, K Ogata, K Yamanaka… - Proceedings of the …, 2018 - pnas.org
Selection of functional spermatozoa plays a crucial role in assisted reproduction. Passage of
spermatozoa through the female reproductive tract requires progressive motility to locate the …
spermatozoa through the female reproductive tract requires progressive motility to locate the …