Colony-stimulating factor 1 receptor (CSF1R, also known as c-FMS) is a receptor tyrosine
kinase. Macrophage colony-stimulating factor (M-CSF) and IL-34 are ligands of CSF1R …

The mononuclear phagocyte system (MPS) is defined as a cell lineage in which committed
marrow progenitors give rise to blood monocytes and tissue macrophages. Here, we discuss …

Microglia are brain-resident macrophages that contribute to central nervous system (CNS)
development, maturation, and preservation. Here, we examine the consequences of …

The proliferation, differentiation and survival of mononuclear phagocytes depend on signals
from the receptor for macrophage colony-stimulating factor, CSF1R. The mammalian Csf1r …

Macrophage colony-stimulating factor (CSF1) is the primary growth factor required for the
control of monocyte and macrophage differentiation, survival, proliferation and renewal …

The mononuclear phagocyte system (MPS) is a family of cells including progenitors,
circulating blood monocytes, resident tissue macrophages, and dendritic cells (DCs) present …

Macrophages are present in all mammalian tissues and coexist with various cell types in
order to respond to different environmental cues. However, the role of these cells has been …

Endometriosis is an estrogen-dependent disease defined by the presence and growth of
functional endometrial-like tissue, glands and stroma, outside the uterine cavity …

Macrophages have a central role in numerous physiological processes, such as immune
defense, maintenance of tissue homeostasis, wound healing, and inflammation. Moreover …

Macrophages are key innate immune cells in the tumor microenvironment (TME) that
regulate primary tumor growth, vascularization, metastatic spread and tumor response to …