Phytochemicals as antimicrobials: prospecting Himalayan medicinal plants as source of alternate medicine to combat antimicrobial resistance

MV Ashraf, S Pant, MAH Khan, AA Shah, S Siddiqui… - Pharmaceuticals, 2023 - mdpi.com
Among all available antimicrobials, antibiotics hold a prime position in the treatment of
infectious diseases. However, the emergence of antimicrobial resistance (AMR) has posed a …

Biotechnology for the production of plant secondary metabolites

R Verpoorte, A Contin, J Memelink - Phytochemistry reviews, 2002 - Springer
The production of plant secondary metabolites by means of large-scale culture of plant cells
in bioreactors is technically feasible. The economy of such a production is the major …

[PDF][PDF] Pharmacognosy in the new millennium: leadfinding and biotechnology

R Verpoorte - Journal of pharmacy and pharmacology, 2000 - researchgate.net
In the past hundred years, synthetic drugs had gradually replaced plant-derived drugs,
except for antibiotics and antitumor drugs. Due;; to the development of expérimentation with …

[SÁCH][B] Metabolic engineering of plant secondary metabolism

R Verpoorte, AW Alfermann - 2000 - books.google.com
Plant secondary metabolism is an economically important source of fine chemicals, such as
drugs, insecticides, dyes, flavours, and fragrances. Moreover, important traits of plants such …

Plant cell suspension cultures: some engineering considerations

PM Kieran, PF MacLoughlin, DM Malone - Journal of Biotechnology, 1997 - Elsevier
Higher plants are the source of a vast array of biochemicals which are used as drugs,
pesticides, flavourings and fragrances. For some of these compounds, plant cell culture can …

Engineering the plant cell factory for secondary metabolite production

R Verpoorte, R van der Heijden, J Memelink - Transgenic research, 2000 - Springer
Plant secondary metabolism is very important for traits such as flower color, flavor of food,
and resistance against pests and diseases. Moreover, it is the source of many fine chemicals …

Changing strategies in natural products chemistry

GA Cordell - Phytochemistry, 1995 - Elsevier
Scientific strategies for the study of natural products from plants have changed substantially
in the past few years for a number of reasons, including advances in technology, new …

Cell and tissue cultures of Catharanthus roseus: A literature survey: II. Updating from 1988 to 1993

PRH Moreno, R van der Heijden… - Plant cell, tissue and organ …, 1995 - Springer
The literature concerning the regulation and the biosynthesis of secondary metabolites in
cell and tissue cultures of Catharanthus roseus is reviewed. The aim of this review is to …

Effects of over-expression of strictosidine synthase and tryptophan decarboxylase on alkaloid production by cell cultures of Catharanthus roseus

C Canel, MI Lopes-Cardoso, S Whitmer, L van der Fits… - Planta, 1998 - Springer
Cells of Catharanthus roseus (L.) G. Don were genetically engineered to over-express the
enzymes strictosidine synthase (STR; EC 4.3. 3.2) and tryptophan decarboxylase (TDC; EC …

Ornamental Exterior versus Therapeutic Interior of Madagascar Periwinkle (Catharanthus roseus): The Two Faces of a Versatile Herb

N Nejat, A Valdiani, D Cahill, YH Tan… - The Scientific World …, 2015 - Wiley Online Library
Catharanthus roseus (L.) known as Madagascar periwinkle (MP) is a legendary medicinal
plant mostly because of possessing two invaluable antitumor terpenoid indole alkaloids …