Chalcone: a privileged structure in medicinal chemistry
Privileged structures have been widely used as an effective template in medicinal chemistry
for drug discovery. Chalcone is a common simple scaffold found in many naturally occurring …
for drug discovery. Chalcone is a common simple scaffold found in many naturally occurring …
Review on the antibacterial mechanism of plant‐derived compounds against multidrug‐resistant bacteria (MDR)
Microbial resistance has progressed rapidly and is becoming the leading cause of death
globally. The spread of antibiotic‐resistant microorganisms has been a significant threat to …
globally. The spread of antibiotic‐resistant microorganisms has been a significant threat to …
Pharmacotherapeutics applications and chemistry of chalcone derivatives
Chalcones have been well examined in the extant literature and demonstrated antibacterial,
antifungal, anti-inflammatory, and anticancer properties. A detailed evaluation of the …
antifungal, anti-inflammatory, and anticancer properties. A detailed evaluation of the …
Recent developments of chalcones as potential antibacterial agents in medicinal chemistry
W Dan, J Dai - European journal of medicinal chemistry, 2020 - Elsevier
Chalcones, containing an α, β-unsaturated ketone fragment, are an important
pharmacologically active agents because of their diverse mechanisms. This review provides …
pharmacologically active agents because of their diverse mechanisms. This review provides …
A review on recent approaches on molecular docking studies of novel compounds targeting acetylcholinesterase in Alzheimer disease
SC Peitzika, E Pontiki - Molecules, 2023 - mdpi.com
Alzheimer's disease (AD), a neurodegenerative brain disorder that affects millions of people
worldwide, is characterized by memory loss and cognitive decline. Low levels of …
worldwide, is characterized by memory loss and cognitive decline. Low levels of …
Molecular targets and anticancer activity of quinoline–chalcone hybrids: Literature review
MFA Mohamed, GEDA Abuo-Rahma - RSC advances, 2020 - pubs.rsc.org
α, β-Unsaturated chalcone moieties and quinoline scaffolds play an important role in
medicinal chemistry, especially in the identification and development of potential anticancer …
medicinal chemistry, especially in the identification and development of potential anticancer …
A comprehensive review on β-lapachone: Mechanisms, structural modifications, and therapeutic potentials
Q Gong, J Hu, P Wang, X Li, X Zhang - European Journal of Medicinal …, 2021 - Elsevier
Abstract β-Lapachone (β-lap, 1), an ortho-naphthoquinone natural product isolated from the
lapacho tree (Tabebuia avellanedae) in many regions of South America, has received …
lapacho tree (Tabebuia avellanedae) in many regions of South America, has received …
Experimental and computational studies on second-and third-order nonlinear optical properties of a novel D-π-A type chalcone derivative: 3-(4-methoxyphenyl)-1-(4 …
The present study reports the theoretical and experimental investigations of linear and
nonlinear optical (static and dynamic) properties of 3-(4-methoxyphenyl)-1-(4-nitrophenyl) …
nonlinear optical (static and dynamic) properties of 3-(4-methoxyphenyl)-1-(4-nitrophenyl) …
Review and chemoinformatic analysis of ferroptosis modulators with a focus on natural plant products
V Stepanić, M Kučerová-Chlupáčová - Molecules, 2023 - mdpi.com
Ferroptosis is a regular cell death pathway that has been proposed as a suitable therapeutic
target in cancer and neurodegenerative diseases. Since its definition in 2012, a few hundred …
target in cancer and neurodegenerative diseases. Since its definition in 2012, a few hundred …
A systematic review on anti-diabetic properties of chalcones
The use of anti-diabetic drugs has been increasing worldwide and the evolution of
therapeutics has been enormous. Still, the currently available anti-diabetic drugs do not …
therapeutics has been enormous. Still, the currently available anti-diabetic drugs do not …