Negative regulation of CPSF6 suppresses the warburg effect and angiogenesis leading to tumor progression via c-myc signaling network: potential therapeutic target …

DY Sim, HJ Lee, CH Ahn, JE Park… - … journal of biological …, 2024‏ - pmc.ncbi.nlm.nih.gov
In this study, we explored the oncogenic mechanism of cleavage and polyadenylation-
specific factor 6 (CPSF6) in hepatocellular carcinoma (HCC). CPSF6 was overexpressed in …

High-throughput transcriptome profiling indicates ribosomal RNAs to be associated with resistance to immunotherapy in non-small cell lung cancer (NSCLC)

MK Moutafi, KM Bates, TN Aung… - Journal for …, 2024‏ - pmc.ncbi.nlm.nih.gov
Background Despite the impressive outcomes with immune checkpoint inhibitor (ICI) in non-
small cell lung cancer (NSCLC), only a minority of the patients show long-term benefits from …

Multidimensional biological characteristics of ground glass nodules

F Chen, J Li, L Li, L Tong, G Wang, X Zou - Frontiers in Oncology, 2024‏ - frontiersin.org
The detection rate of ground glass nodules (GGNs) has increased in recent years because
of their malignant potential but relatively indolent biological behavior; thus, correct GGN …

[HTML][HTML] RBM10 Mutation as a Potential Negative Prognostic/Predictive Biomarker to Therapy in Non-Small-Cell Lung Cancer

A Reyes, M Afkhami, E Massarelli, J Fricke… - Clinical Lung Cancer, 2024‏ - Elsevier
Background According to WHO, lung cancer is the leading cause of cancer-related death
worldwide, but treatment has advanced in the last decade. The widespread use of Next …