Organoids and cells in organ‐on‐chip platforms replicate higher‐level anatomical,
physiological, or pathological states of tissues and organs. These technologies are widely …

Metal elements represent some of the most fundamental chemical building blocks of life and
are required to sustain the growth, development, and sustenance of all living organisms and …

Copper is an essential micronutrient and also a regulated product used in organic and in
conventional farming pest management. Both deficiency and excessive exposure to copper …

ABSTRACT A 7 yr old castrated male Cavalier King Charles spaniel presented for
evaluation of liver enzyme elevations. Abdominal ultrasound revealed a small liver with …

Studies with Wilson disease model mice that accumulate excessive copper, due to a
dysfunctional ATP7B “copper pump” resulting in decreased biliary excretion, showed that …

A general principle in all cells in the body is that an essential metal–here copper–is taken up
at the plasma membrane, directed through cellular compartments for use in specific …

Metals dominate the inorganic side of the universe. In fact, out of the 98 naturally occurring
elements identified so far, 71 are metals and the rest are non-metals or metalloids …

Objectives The aim of this study was to assess laser ablation-inductively coupled plasma-
mass spectrometry (LA-ICP-MS) as a tool for measuring concentrations and determining …

Abstract The Panel on Additives and Products or Substances used in Animal Feed
(FEEDAP) reviewed (i) the copper requirements of food‐producing and pet animals,(ii) the …

Simple Summary Establishing reference ranges for essential and toxic trace elements in
dogs is important to assess health status and to enable assessments of the background …