The chemotherapeutic use of cisplatin is limited by its severe side effects. In this study, by
conducting different omics data analyses, we demonstrated that cisplatin induces cell death …

Testicular germ cell tumors (GCTs) are highly curable malignancies. Excellent survival rates
in patients with metastatic disease can be attributed to the exceptional sensitivity of GCTs to …

Testicular germ cell tumors share a marked sensitivity to cisplatin, contributing to their
overall good prognosis. However, a subset of patients develop resistance to platinum-based …

A series of organometallic AuI N‐heterocyclic carbene (NHC) complexes was synthesized
and characterized for anticancer activity in four human cancer cell lines. The compounds' …

Although the skin production of vitamin D is initiated by ultraviolet radiation type B (UVB), the
role vitamin D plays in antioxidative or pro-oxidative responses remains to be elucidated …

Testicular cancer is the most frequent solid malignant tumour type in men 20–40 years of
age. At the time of diagnosis up to 50% of the patients suffer from metastatic disease. In …

Abstract Purpose of Review Testicular germ cell tumors (TGCTs) represent the most
common solid tumors affecting young men. Majority of TGCTs respond well to cisplatin …

ID1 (inhibitor of differentiation/DNA binding 1) acts an important role in metastasis,
tumorigenesis, and maintenance of cell viability. It has been shown that the up-regulation of …

Although rare cancers overall, testicular germ cell tumors (TGCTs) are the most common
type of cancer in young males below 40 years of age. Both subtypes of TGCTs, ie …

The majority of patients with advanced ovarian germ cell cancer are treated by cisplatin-
based chemotherapy. Despite adequate first-line treatment, nearly one third of patients …