Wnt/β-catenin-driven EMT regulation in human cancers

W Xue, L Yang, C Chen, M Ashrafizadeh, Y Tian… - Cellular and Molecular …, 2024 - Springer
Metastasis accounts for 90% of cancer-related deaths among the patients. The
transformation of epithelial cells into mesenchymal cells with molecular alterations can occur …

Adipocyte pyroptosis occurs in omental tumor microenvironment and is associated with chemoresistance of ovarian cancer

CN Lin, YL Liang, HF Tsai, PY Wu, LY Huang… - Journal of biomedical …, 2024 - Springer
Background Ovarian carcinoma (OC) is a fatal malignancy, with most patients experiencing
recurrence and resistance to chemotherapy. In contrast to hematogenous metastasizing …

Aberrant angiogenic signaling pathways: accomplices in ovarian cancer progression and treatment

W Zhou, T Zeng, J Chen, X Tang, Y Yuan, D Hu… - Cellular …, 2024 - Elsevier
Ovarian cancer is one of the most common malignant tumors in women, and treatment
options are limited. Despite efforts to adjust cancer treatment models and develop new …

[HTML][HTML] Evaluation of the Efficacy of a Full-Spectrum Low-THC Cannabis Plant Extract Using In Vitro Models of Inflammation and Excitotoxicity

E Ross-Munro, E Isikgel, B Fleiss - Biomolecules, 2024 - mdpi.com
Evidence has accumulated that Cannabis-derived compounds have the potential to treat
neuroinflammatory changes present in neurodevelopmental conditions such as autism …

Safety and efficacy of orally administered full-spectrum medicinal Cannabis plant extract 0.08% THC (NTI-164) in children with autism spectrum disorder: an open …

D El-Sukkari, K Sharma, B Fleiss, DL Braganza… - MedRxiv, 2023 - medrxiv.org
Autism spectrum disorder (ASD) is commonly associated with debilitating comorbidities
impacting the well-being of affected children and their families. Some children with ASD …

Secondary metabolite profiles and anti‐SARS‐CoV‐2 activity of ethanolic extracts from nine genotypes of Cannabis sativa L.

E Schadich, D Kaczorová, T Béres… - Archiv der …, 2025 - Wiley Online Library
This study deals with the comprehensive phytochemical composition and antiviral activity
against SARS‐CoV‐2 of acidic (non‐decarboxylated) and neutral (decarboxylated) …

[HTML][HTML] Cannabigerol Treatment Shows Antiproliferative Activity and Causes Apoptosis of Human Colorectal Cancer Cells

JH Park, YN Hwang, HH Na, DY Kim… - Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Objectives To determine growth inhibitory and anti-cancer effects of Cannabigerol (CBG) in
human colorectal cancer cells. Methods Anti-proliferative effect of CBG was examined using …

Cell death induction and intracellular vesicle formation in human colorectal cancer cells treated with Δ9-Tetrahydrocannabinol

YN Hwang, IS Kwon, JH Park, HH Na, TH Kwon… - Genes & Genomics, 2023 - Springer
Abstract Background Δ9-Tetrahydrocannabinol (Δ9-THC) is a principal psychoactive extract
of Cannabis sativa and has been traditionally used as palliative medicine for neuropathic …

Integrated transcriptome and cell phenotype analysis suggest involvement of PARP1 cleavage, Hippo/Wnt, TGF-β and MAPK signaling pathways in ovarian cancer …

N Shalev, M Kendall, N Kumar, S Tiwari, SM Anil… - Frontiers in …, 2024 - frontiersin.org
Introduction: Cannabis sativa is utilized mainly for palliative care worldwide. Ovarian cancer
(OC) is a lethal gynecologic cancer. A particular cannabis extract fraction ('F7′) and the …