Biology of the heat shock response and protein chaperones: budding yeast (Saccharomyces cerevisiae) as a model system

J Verghese, J Abrams, Y Wang… - … and molecular biology …, 2012 - journals.asm.org
The eukaryotic heat shock response is an ancient and highly conserved transcriptional
program that results in the immediate synthesis of a battery of cytoprotective genes in the …

Response mechanisms of Saccharomyces cerevisiae to the stress factors present in lignocellulose hydrolysate and strategies for constructing robust strains

B Li, N Liu, X Zhao - Biotechnology for Biofuels and Bioproducts, 2022 - Springer
Bioconversion of lignocellulosic biomass to biofuels such as bioethanol and high value-
added products has attracted great interest in recent decades due to the carbon neutral …

Cellular noise regulons underlie fluctuations in Saccharomyces cerevisiae

J Stewart-Ornstein, JS Weissman, H El-Samad - Molecular cell, 2012 - cell.com
Stochasticity is a hallmark of cellular processes, and different classes of genes show large
differences in their cell-to-cell variability (noise). To decipher the sources and consequences …

Saccharomyces cerevisiae biomass as a source of next‐generation food preservatives: Evaluating potential proteins as a source of antimicrobial peptides

PR Pereira, CS Freitas… - … reviews in food science …, 2021 - Wiley Online Library
Saccharomyces cerevisiae is the main biotechnological tool for the production of Baker's or
Brewer's biomasses, largely applied in beverage and fermented‐food production. Through …

Molecular mechanisms and highly functional development for stress tolerance of the yeast Saccharomyces cerevisiae

H Takagi - Bioscience, Biotechnology, and Biochemistry, 2021 - academic.oup.com
In response to environmental stress, microorganisms adapt to drastic changes while
exerting cellular functions by controlling gene expression, metabolic pathways, enzyme …

Mitochondria–cytosol–nucleus crosstalk: learning from Saccharomyces cerevisiae

N Guaragnella, LP Coyne, XJ Chen… - FEMS yeast …, 2018 - academic.oup.com
Mitochondria are key cell organelles with a prominent role in both energetic metabolism and
the maintenance of cellular homeostasis. Since mitochondria harbor their own genome …

Regulations and functions of proline utilization in yeast Saccharomyces cerevisiae

A Nishimura - Bioscience, Biotechnology, and Biochemistry, 2024 - academic.oup.com
The quality of alcoholic beverages strongly depends on the metabolic characteristics of the
yeast cells being used. To control the aroma and the taste of alcoholic beverages, as well as …

Ploidy influences the functional attributes of de novo lager yeast hybrids

K Krogerus, M Arvas, M De Chiara… - Applied microbiology …, 2016 - Springer
The genomes of hybrid organisms, such as lager yeast (Saccharomyces cerevisiae×
Saccharomyces eubayanus), contain orthologous genes, the functionality and effect of …

Fasting regulates EGR1 and protects from glucose-and dexamethasone-dependent sensitization to chemotherapy

S Di Biase, HS Shim, KH Kim, M Vinciguerra… - PLoS …, 2017 - journals.plos.org
Fasting reduces glucose levels and protects mice against chemotoxicity, yet drugs that
promote hyperglycemia are widely used in cancer treatment. Here, we show that …

Nuclear Hsp104 safeguards the dormant translation machinery during quiescence

V Kohler, A Kohler, LL Berglund, X Hao… - Nature …, 2024 - nature.com
The resilience of cellular proteostasis declines with age, which drives protein aggregation
and compromises viability. The nucleus has emerged as a key quality control compartment …