Acute chorioamnionitis and funisitis: definition, pathologic features, and clinical significance

CJ Kim, R Romero, P Chaemsaithong… - American journal of …, 2015 - Elsevier
Acute inflammatory lesions of the placenta consist of diffuse infiltration of neutrophils at
different sites in the organ. These lesions include acute chorioamnionitis, funisitis, and …

The enigma of spontaneous preterm birth

LJ Muglia, M Katz - New England Journal of Medicine, 2010 - Mass Medical Soc
The world's preterm birth rate continues to increase. In 2006, preterm births accounted for
12.8% of live births in the United States. Only about half the cases of prematurity result from …

The placenta harbors a unique microbiome

K Aagaard, J Ma, KM Antony, R Ganu… - Science translational …, 2014 - science.org
Humans and their microbiomes have coevolved as a physiologic community composed of
distinct body site niches with metabolic and antigenic diversity. The placental microbiome …

Vaginal progesterone in women with an asymptomatic sonographic short cervix in the midtrimester decreases preterm delivery and neonatal morbidity: a systematic …

R Romero, K Nicolaides, A Conde-Agudelo… - American journal of …, 2012 - Elsevier
OBJECTIVE: To determine whether the use of vaginal progesterone in asymptomatic women
with a sonographic short cervix (≤ 25 mm) in the midtrimester reduces the risk of preterm …

Periodontal disease and adverse pregnancy outcomes

YA Bobetsis, F Graziani, M Gürsoy… - Periodontology …, 2020 - Wiley Online Library
Periodontal diseases are considered not only to affect tooth‐supporting tissues but also to
have a cause‐and‐effect relationship with various systemic diseases and conditions, such …

Does the human placenta delivered at term have a microbiota? Results of cultivation, quantitative real-time PCR, 16S rRNA gene sequencing, and metagenomics

KR Theis, R Romero, AD Winters, JM Greenberg… - American journal of …, 2019 - Elsevier
Background The human placenta has been traditionally viewed as sterile, and microbial
invasion of this organ has been associated with adverse pregnancy outcomes. Yet, recent …

Chorioamnionitis and neonatal outcomes

VG Jain, KA Willis, A Jobe, N Ambalavanan - Pediatric research, 2022 - nature.com
Chorioamnionitis or intrauterine inflammation is a frequent cause of preterm birth.
Chorioamnionitis can affect almost every organ of the develo** fetus. Multiple microbes …

Designing liquid‐infused surfaces for medical applications: a review

C Howell, A Grinthal, S Sunny, M Aizenberg… - Advanced …, 2018 - Wiley Online Library
The development of new technologies is key to the continued improvement of medicine,
relying on comprehensive materials design strategies that can integrate advanced …

Adverse pregnancy outcomes (APO s) and periodontal disease: pathogenic mechanisms

PN Madianos, YA Bobetsis… - Journal of clinical …, 2013 - Wiley Online Library
Aim To evaluate the evidence on potential biological pathways underlying the possible
association between periodontal disease (PD) and adverse pregnancy outcomes (APO s) …

Identification of intracellular bacteria in the basal plate of the human placenta in term and preterm gestations

MJ Stout, B Conlon, M Landeau, I Lee, C Bower… - American journal of …, 2013 - Elsevier
OBJECTIVE: Bacteria have been identified in different regions of the placenta. Here, we
tested the hypothesis that the maternal basal plate of the placenta harbors microbes that …