Highlights•Surface engineering of SPION determines their in vivo performance.•Targeting
mechanisms of SPION imaging are summarized.•Clinical trial information related to SPION …

Superparamagnetic iron oxide nanoparticles (SPIO) can be used to image physiological
processes and anatomical, cellular and molecular changes in diseases. The clinical …

Engineering and functionalizing magnetic nanoparticles have been an area of the extensive
research and development in the biomedical and nanomedicine fields. Because their …

Purpose Conventional MRI using contrast agents is semiquantitative because it is inherently
sensitive to extravoxular susceptibility artifacts, field inhomogeneity, partial voluming …

The nexus of advanced technology and medical therapeutics has ushered in a
transformative epoch in contemporary medicine. Within this arena, Magnetic Resonance …

Stem cell based therapies have critical impacts on treatments and cures of diseases such as
neurodegenerative or cardiovascular disease. In vivo tracking of stem cells labeled with …

A method called Quantitative Ultra-Short Time-to-Echo Contrast Enhanced (QUTE-CE)
Magnetic Resonance Imaging (MRI) which utilizes superparamagnetic iron oxide …

Purpose The purpose of this study was to investigate an ultrashort echo time (UTE) imaging
approach for improving the detection of receptor targeted magnetic nanoparticles in cancer …

The past three decades have seen numerous advances in tissue engineering and
regenerative medicine (TERM) therapies. However, despite the successes there is still much …

Inorganic do** was used to create flexible, paramagnetic nanoparticle contrast agents for
in vivo molecular magnetic resonance imaging (MRI) with low transverse relaxivity (r2). Most …