Where is cingulate cortex? A cross-species view
To compare findings across species, neuroscience relies on cross-species homologies,
particularly in terms of brain areas. For cingulate cortex, a structure implicated in behavioural …
particularly in terms of brain areas. For cingulate cortex, a structure implicated in behavioural …
Common neurocircuitry mediating drug and fear relapse in preclinical models
Background Comorbidity of anxiety disorders, stressor-and trauma-related disorders, and
substance use disorders is extremely common. Moreover, therapies that reduce pathological …
substance use disorders is extremely common. Moreover, therapies that reduce pathological …
Beyond the hippocampus: the role of parahippocampal-prefrontal communication in context-modulated behavior
X Peng, RD Burwell - Neurobiology of learning and memory, 2021 - Elsevier
Multiple paradigms indicate that the physical environment can influence spontaneous and
learned behavior. In rodents, context-dependent behavior is putatively supported by the …
learned behavior. In rodents, context-dependent behavior is putatively supported by the …
Neural correlates and determinants of approach–avoidance conflict in the prelimbic prefrontal cortex
The recollection of environmental cues associated with threat or reward allows animals to
select the most appropriate behavioral responses. Neurons in the prelimbic (PL) cortex …
select the most appropriate behavioral responses. Neurons in the prelimbic (PL) cortex …
Distinct roles of prelimbic and infralimbic proBDNF in extinction of conditioned fear
W Sun, X Li, L An - Neuropharmacology, 2018 - Elsevier
Brain-derived neurotrophic factor (BDNF) has been investigated for its positive role in
regulation of fear acquisition and memory. The precursor of BDNF, proBDNF, has been …
regulation of fear acquisition and memory. The precursor of BDNF, proBDNF, has been …
Prelimbic and infralimbic cortical inactivations attenuate contextually driven discriminative responding for reward
S Riaz, P Puveendrakumaran, D Khan, S Yoon… - Scientific reports, 2019 - nature.com
The infralimbic (IL) and prelimbic (PL) cortices of the medial prefrontal cortex (mPFC) have
been shown to differentially control context-dependent behavior, with the PL implicated in …
been shown to differentially control context-dependent behavior, with the PL implicated in …
The inhibitory avoidance discrimination task to investigate accuracy of memory
E Atucha, B Roozendaal - Frontiers in Behavioral Neuroscience, 2015 - frontiersin.org
The present study was aimed at develo** a new inhibitory avoidance task, based on
training and/or testing rats in multiple contexts, to investigate accuracy of memory. In the first …
training and/or testing rats in multiple contexts, to investigate accuracy of memory. In the first …
The prelimbic cortex uses contextual cues to modulate responding towards predictive stimuli during fear renewal
Previous research suggests the prelimbic (PL) cortex is involved in expression of
conditioned fear (Burgos-Robles, Vidal-Gonzalez, & Quirk, 2009; Corcoran & Quirk, 2007) …
conditioned fear (Burgos-Robles, Vidal-Gonzalez, & Quirk, 2009; Corcoran & Quirk, 2007) …
Differential fear conditioning generates prefrontal neural ensembles of safety signals
A Corches, A Hiroto, TW Bailey, JH Speigel III… - Behavioural brain …, 2019 - Elsevier
Fear discrimination is critical for survival, while fear generalization is effective for avoiding
dangerous situations. Overgeneralized fear is a typical symptom of anxiety disorders …
dangerous situations. Overgeneralized fear is a typical symptom of anxiety disorders …
Comparison of behavioral and brain indices of fear renewal during a standard vs. novel immersive reality Pavlovian fear extinction paradigm in healthy adults
Pavlovian conditioning paradigms model the learned fear associations inherent in
posttraumatic stress disorder, including the renewal of inappropriate fear responses …
posttraumatic stress disorder, including the renewal of inappropriate fear responses …