Silicones in dermatological topical drug formulation: Overview and advances

HT Sounouvou, A Lechanteur, G Piel… - International journal of …, 2022 - Elsevier
Silicones, more specifically those of the polydimethylsiloxane type, have been widely used
in the pharmaceutical industry for decades, particularly in topical applications. In the …

Molecular insight into drug-loading capacity of PEG–PLGA nanoparticles for itraconazole

N Wilkosz, G Łazarski, L Kovacik… - The Journal of …, 2018 - ACS Publications
Nanoparticles made of amphiphilic block copolymers comprising biodegradable core-
forming blocks are very attractive for the preparation of drug-delivery systems with sustained …

Polycation–anionic lipid membrane interactions

W Kopec, A Zak, D Jamróz, R Nakahata, S Yusa… - Langmuir, 2020 - ACS Publications
Natural or synthetic polycations are used as biocides or as drug/gene carriers.
Understanding the interactions between these macromolecules and cell membranes at the …

Encapsulation of Curcumin in Polystyrene-Based Nanoparticles—Drug Loading Capacity and Cytotoxicity

M Zatorska-Płachta, G Łazarski, U Maziarz, A Foryś… - ACS …, 2021 - ACS Publications
Nanoparticles made of amphiphilic block copolymers are commonly used in the preparation
of nano-sized drug delivery systems. Poly (styrene)–block–poly (acrylic acid)(PS–PAA) …

[HTML][HTML] Molecular insights into the self-assembly of hydrophobically modified chondroitin sulfate in aqueous media

A Żak, G Łazarski, M Wytrwal-Sarna, D Jamróz… - Carbohydrate …, 2022 - Elsevier
Hydrophobically modified chondroitin sulfate (CS) is widely used in the preparation of nano-
sized drug delivery systems. Herein, the behavior of amphiphilic CSs in aqueous media and …

Molecular mechanism of polycation-induced pore formation in biomembranes

N Awasthi, W Kopec, N Wilkosz, D Jamróz… - ACS Biomaterials …, 2018 - ACS Publications
Polycations are an attractive class of macromolecules with promising applications as
drug/gene carriers and biocides. The chemical structure and concentration of a polycation …

Drug-loading capacity of polylactide-based micro-and nanoparticles–Experimental and molecular modeling study

M Zatorska, G Łazarski, U Maziarz, N Wilkosz… - International Journal of …, 2020 - Elsevier
Micro-and nanostructures prepared from biodegradable homopolymers and amphiphilic
block copolymers (AmBCs) have found application as drug-delivery systems (DDSs). The …

Interactions of polyethylenimines with zwitterionic and anionic lipid membranes

U Kwolek, D Jamróz, M Janiczek, M Nowakowska… - Langmuir, 2016 - ACS Publications
Interactions between polyethylenimines (PEIs) and phospholipid membranes are of
fundamental importance for various biophysical applications of these polymers such as …

Effect of polycation structure on interaction with lipid membranes

N Wilkosz, D Jamróz, W Kopec, K Nakai… - The Journal of …, 2017 - ACS Publications
Interaction of polycations with lipid membranes is a very important issue in many biological
and medical applications such as gene delivery or antibacterial usage. In this work, we …

Interactions of a hydrophobically modified polycation with zwitterionic lipid membranes

M Kepczynski, D Jamróz, M Wytrwal, J Bednar… - Langmuir, 2012 - ACS Publications
The interactions between synthetic polycations and phospholipid bilayers play an important
role in some biophysical applications such as gene delivery or antibacterial usage. Despite …