[HTML][HTML] Determinants and outcomes of mitochondrial dynamics

R Quintana-Cabrera, L Scorrano - Molecular Cell, 2023 - cell.com
Mitochondria are not only central organelles in metabolism and energy conversion but are
also platforms for cellular signaling cascades. Classically, the shape and ultrastructure of …

Mechanisms of mitochondrial respiratory adaptation

CF Bennett, P Latorre-Muro, P Puigserver - Nature Reviews Molecular …, 2022 - nature.com
Mitochondrial energetic adaptations encompass a plethora of conserved processes that
maintain cell and organismal fitness and survival in the changing environment by adjusting …

Distinct fission signatures predict mitochondrial degradation or biogenesis

T Kleele, T Rey, J Winter, S Zaganelli, D Mahecic… - Nature, 2021 - nature.com
Mitochondrial fission is a highly regulated process that, when disrupted, can alter
metabolism, proliferation and apoptosis,–. Dysregulation has been linked to …

Molecular mechanisms of mitochondrial dynamics

LC Tábara, M Segawa, J Prudent - Nature Reviews Molecular Cell …, 2024 - nature.com
Mitochondria not only synthesize energy required for cellular functions but are also involved
in numerous cellular pathways including apoptosis, calcium homoeostasis, inflammation …

Mitochondrial quality control in health and in Parkinson's disease

MA Eldeeb, RA Thomas, MA Ragheb… - Physiological …, 2022 - journals.physiology.org
As a central hub for cellular metabolism and intracellular signaling, the mitochondrion is a
pivotal organelle, dysfunction of which has been linked to several human diseases including …

Mitochondria as cellular and organismal signaling hubs

K Shen, CL Pender, R Bar-Ziv, H Zhang… - Annual review of cell …, 2022 - annualreviews.org
Mitochondria are traditionally known as the powerhouse of the cell, but their functions
extend far beyond energy production. They are vital in cellular and organismal pathways …

[HTML][HTML] Mitochondrial fusion and fission: The fine-tune balance for cellular homeostasis

M Adebayo, S Singh, AP Singh… - FASEB journal: official …, 2021 - ncbi.nlm.nih.gov
Mitochondria are highly dynamic, maternally inherited cytoplasmic organelles, which fulfill
cellular energy demand through the oxidative phosphorylation system. Besides, they play an …

MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control

T König, H Nolte, MJ Aaltonen, T Tatsuta, M Krols… - Nature cell …, 2021 - nature.com
Mitochondrial-derived vesicles (MDVs) are implicated in diverse physiological processes—
for example, mitochondrial quality control—and are linked to various neurodegenerative …

The cell biology of mitochondrial membrane dynamics

M Giacomello, A Pyakurel, C Glytsou… - Nature reviews Molecular …, 2020 - nature.com
Owing to their ability to efficiently generate ATP required to sustain normal cell function,
mitochondria are often considered the 'powerhouses of the cell'. However, our …

The role of mitochondrial fission in cardiovascular health and disease

JM Quiles, ÅB Gustafsson - Nature Reviews Cardiology, 2022 - nature.com
Mitochondria are organelles involved in the regulation of various important cellular
processes, ranging from ATP generation to immune activation. A healthy mitochondrial …