Structure of the native myosin filament in the relaxed cardiac sarcomere

D Tamborrini, Z Wang, T Wagner, S Tacke, M Stabrin… - Nature, 2023 - nature.com
The thick filament is a key component of sarcomeres, the basic units of striated muscle.
Alterations in thick filament proteins are associated with familial hypertrophic …

An ultra-light Mg-Li alloy with exceptional elastic modulus, high strength, and corrosion-resistance

G Tian, J Wang, S Wang, C Xue, X Yang… - Materials Today …, 2023 - Elsevier
In this paper, a new Mg-Li alloy with exceptional Young's modulus, great specific strength,
and outstanding corrosion-resistance has been successfully developed, exceeding any …

Semantic segmentation of the micro-structure of strain-hardening cement-based composites (SHCC) by applying deep learning on micro-computed tomography scans

R Lorenzoni, I Curosu, S Paciornik… - Cement and Concrete …, 2020 - Elsevier
Considering the multi-phase constitutive nature of strain-hardening cement-based
composites (SHCC) and the decided influence of their micromechanics on overall material …

Three-dimensional analysis of particle distribution on filter layers inside N95 respirators by deep learning

HR Lee, L Liao, W **ao, A Vailionis, AJ Ricco… - Nano …, 2020 - ACS Publications
The global COVID-19 pandemic has changed many aspects of daily lives. Wearing personal
protective equipment, especially respirators (face masks), has become common for both the …

Systematic transmission electron microscopy‐based identification and 3D reconstruction of cellular degradation machinery

K Neikirk, Z Vue, P Katti, BI Rodriguez… - Advanced …, 2023 - Wiley Online Library
Various intracellular degradation organelles, including autophagosomes, lysosomes, and
endosomes, work in tandem to perform autophagy, which is crucial for cellular homeostasis …

The role and risks of selective adaptation in extreme coral habitats

F Scucchia, P Zaslansky, C Boote, A Doheny… - Nature …, 2023 - nature.com
The alarming rate of climate change demands new management strategies to protect coral
reefs. Environments such as mangrove lagoons, characterized by extreme variations in …

Disruption of the mitochondrial network in a mouse model of Huntington's disease visualized by in-tissue multiscale 3D electron microscopy

E Martin-Solana, L Casado-Zueras, TE Torres… - Acta Neuropathologica …, 2024 - Springer
Huntington's disease (HD) is an inherited neurodegenerative disorder caused by an
expanded CAG repeat in the coding sequence of huntingtin protein. Initially, it predominantly …

Effect of cooling rate on carbides in directionally solidified nickel-based single crystal superalloy: X-ray tomography and U-net CNN quantification

K Liu, J Wang, Y Yang, Y Zhou - Journal of Alloys and Compounds, 2021 - Elsevier
X-ray computed microtomography (X-CT) and U-net convolutional neural network (U-net
CNN) were used to characterize and segment the three-dimensional structure of MC and M …

Achieving ultra-high stiffness by solidifying and precipitating micro-compounds in HCP/BCC dual matrix of a new Mg-Li alloy

G Tian, J Wang, S Wang, C Xue, X Yang, H Su… - Journal of Alloys and …, 2023 - Elsevier
One of the major obstacles restricting the wide applications of Mg alloys is their low Young's
modulus at∼ 45 GPa, which is uncompetitive to Al alloy over 60 GPa. To resolve this issue …

The petrous bone contains high concentrations of osteocytes: One possible reason why ancient DNA is better preserved in this bone

J Ibrahim, V Brumfeld, Y Addadi, S Rubin, S Weiner… - PloS one, 2022 - journals.plos.org
The characterization of ancient DNA in fossil bones is providing invaluable information on
the genetics of past human and other animal populations. These studies have been aided …