The vascular network is established and maintained through the processes of
vasculogenesis and angiogenesis, which are tightly regulated during embryonic and …

The human dedicator of cytokinesis (DOCK) family consists of 11 structurally conserved
proteins that serve as atypical RHO guanine nucleotide exchange factors (RHO GEFs) …

Loss-of-function alleles are a pertinent source of genetic variation with the potential to
contribute to adaptation. Cave-adapted organisms exhibit striking loss of ancestral traits …

Background The effect of DOCK1 gene on the biological behavior of endometrial carcinoma
cells and its related pathway has not been reported. Methods The immunohistochemical …

Peripheral nervous system development involves a tight coordination of neuronal birth and
death and a substantial remodelling of the myelinating glia cytoskeleton to achieve myelin …

Schwann cells (SCs) migrate along peripheral axons and divide intensively to generate the
right number of cells prior to axonal ensheathment; however, little is known regarding the …

The vertebrate peripheral nervous system (PNS) is an intricate network that conveys sensory
and motor information throughout the body. During development, extracellular cues direct …

Abstract Background Schwann cells (SCs) are specialized glial cells of the peripheral
nervous system that produce myelin and promote fast action potential propagation. In order …

Schwann cells, the myelinating glia of the peripheral nervous system (PNS), are critical for
myelin development, maintenance, and repair. Rac1 is a known regulator of radial sorting, a …

Background The 10q26 subtelomeric microdeletion syndrome is a rare and clinically
heterogeneous disorder. The precise relationships between the causative genes and the …