Objectives The aim of this prospective multicenter study was to identify the optimal approach
for simple and fast fractional flow reserve (FFR) computation from radiographic coronary …

Fractional flow reserve is the current invasive gold standard for assessing the ischemic
potential of an angiographically intermediate coronary stenosis. Procedural cost and time …

Despite considerable improvement in diagnostic modalities and therapeutic options over the
last few decades, the global burden of ischemic heart disease is steadily rising, remaining a …

Aims: Randomised controlled trials have reported instantaneous wave-free ratio (iFR) to be
non-inferior to fractional flow reserve (FFR) for major adverse cardiovascular events at one …

A coronary angiography-derived index of microvascular resistance (caIMR) is proposed for
physiological assessment of microvasular diseases in coronary circulation. The aim of the …

Abstract Background and Aims Guidelines recommend revascularization of intermediate
epicardial artery stenosis to be guided by evidence of ischaemia. Fractional flow reserve …

Objectives: This work compares the diagnostic performance of adenosine-free coronary
pressure wire indices based on lesion location. Background: Several adenosine-free …

Aims The instantaneous wave-free ratio (iFR) and whole-cycle Pd/Pa investigate coronary
physiology during non-hyperaemic conditions. To test for unique physiologic properties of …

Background The invasive physiologic index such as fractional flow reserve (FFR) or
instantaneous wave-free ratio (iFR) is used in clinical practice to identify ischemia-causing …

Background—Distal coronary to aortic pressure ratio (Pd/Pa) and instantaneous wave-free
ratio (iFR) are indices of functional significance of a coronary stenosis measured without …