Nerve guidance conduit development for primary treatment of peripheral nerve transection injuries: A commercial perspective
BJ Parker, DI Rhodes, CM O'Brien, AE Rodda… - Acta Biomaterialia, 2021 - Elsevier
Commercial nerve guidance conduits (NGCs) for repair of peripheral nerve discontinuities
are of little use in gaps larger than 30 mm, and for smaller gaps they often fail to compete …
are of little use in gaps larger than 30 mm, and for smaller gaps they often fail to compete …
Fundamentals and current strategies for peripheral nerve repair and regeneration
A body of evidence indicates that peripheral nerves have an extraordinary yet limited
capacity to regenerate after an injury. Peripheral nerve injuries have confounded …
capacity to regenerate after an injury. Peripheral nerve injuries have confounded …
Fabrication of ECM protein coated hollow collagen channels to study peripheral nerve regeneration
Peripheral nerve injury is a prevalent clinical problem that often leads to lifelong disability
and reduced quality of life. Although peripheral nerves can regenerate, recovery after severe …
and reduced quality of life. Although peripheral nerves can regenerate, recovery after severe …
Effects of ECM proteins (laminin, fibronectin, and type IV collagen) on the biological behavior of Schwann cells and their roles in the process of remyelination after …
P Yu, G Zhang, B Hou, E Song, J Wen, Y Ba… - … in Bioengineering and …, 2023 - frontiersin.org
Introduction: It is important to note that complete myelination and formation of myelinated
fibers are essential for functional nerve regeneration after peripheral nerve injury (PNI) …
fibers are essential for functional nerve regeneration after peripheral nerve injury (PNI) …
Development and in vitro differentiation of Schwann cells
SJ Hörner, N Couturier, DC Gueiber, M Hafner… - Cells, 2022 - mdpi.com
Schwann cells are glial cells of the peripheral nervous system. They exist in several
subtypes and perform a variety of functions in nerves. Their derivation and culture in vitro are …
subtypes and perform a variety of functions in nerves. Their derivation and culture in vitro are …
Surface Modification of Nerve Guide Conduits with ECM Coatings and Investigating Their Impact on Schwann Cell Response
L Pinzon‐Herrera, J Magness… - Advanced …, 2024 - Wiley Online Library
In this study, layer‐by‐layer coatings composed of heparin and collagen are proposed as an
extracellular mimetic environment on nerve guide conduits (NGC) to modulate the behavior …
extracellular mimetic environment on nerve guide conduits (NGC) to modulate the behavior …
Coating materials for neural stem/progenitor cell culture and differentiation
D Liu, N Pavathuparambil Abdul Manaph… - Stem Cells and …, 2020 - liebertpub.com
Neural stem/progenitor cells (NSPCs) have a potential to treat various neurological
diseases, such as Parkinson's Disease, Alzheimer's Disease, and Spinal Cord Injury …
diseases, such as Parkinson's Disease, Alzheimer's Disease, and Spinal Cord Injury …
In Vitro Models for Peripheral Nerve Regeneration
J Tusnim, P Kutuzov… - Advanced Healthcare …, 2024 - Wiley Online Library
Peripheral nerve injury (PNI) resulting in lesions is highly prevalent clinically, but current
therapeutic approaches fail to provide satisfactory outcomes in many patients. While …
therapeutic approaches fail to provide satisfactory outcomes in many patients. While …
Contact-triggered lipofection from multilayer films designed as surfaces for in situ transfection strategies in tissue engineering
C Husteden, F Doberenz, N Goergen… - … applied materials & …, 2020 - ACS Publications
Biomaterials, which release active compounds after implantation, are an essential tool for
targeted regenerative medicine. In this study, thin multilayer films loaded with lipid/DNA …
targeted regenerative medicine. In this study, thin multilayer films loaded with lipid/DNA …
Microfluidic wound-healing assay for ECM and microenvironment properties on microglia BV2 cells migration
Microglia cells, as the resident immune cells of the central nervous system (CNS), are highly
motile and migratory in development and pathophysiological conditions. During their …
motile and migratory in development and pathophysiological conditions. During their …