Hyaluronic acid (HA), a biodegradable, biocompatible and non-immunogenic therapeutic
polymer is a key component of the cartilage extracellular matrix (ECM) and has been widely …

Hydrogels have immense potential in revolutionizing central nervous system (CNS) drug
delivery, improving outcomes for neurological disorders. They serve as promising tools for …

Rheumatoid arthritis (RA) is a chronic inflammatory illness affecting the joints. The
characteristic of RA is gradual joint deterioration. Current RA treatment alleviates signs such …

It is increasingly urgent to develop new therapeutic systems to combat the spreading and
evolution of various pathologies globally. Nonspecific therapies and/or insufficient …

Rheumatoid arthritis (RA) is one of the most prevalent life-long autoimmune diseases with
an unknown genesis. It primarily causes chronic inflammation, pain, and synovial joint …

Purpose: Rheumatoid arthritis, a chronic and progressive inflammation condition in the
joints, has significantly reduced the patient quality of life and life expectancy. Crucially, there …

Rheumatoid arthritis (RA) and osteoarthritis (OA) are disabling musculoskeletal disorders
that affect joints and cartilage and may lead to bone degeneration. Conventional delivery of …

In this study, we designed novel self-healing hydrogels (CMC/DAQP-HGs) using
carboxymethyl chitosan (CMC) and dialdehyde quaternized pullulan (DAQP), aimed at …

The intra-articular administration of conventional drug solutions or dispersions in joint
diseases such as osteoarthritis has a relatively short retention time and, therefore, limited …

Rheumatoid arthritis (RA) is a chronic, prevalent, immune-mediated, inflammatory, joint
disorder affecting millions of people worldwide. Despite current treatment options, many …