Myelinated nerve fibers have evolved to enable fast and efficient transduction of electrical
signals in the nervous system. To act as an electric insulator, the myelin sheath is formed as …

Myelination of axons in the nervous system of vertebrates enables fast, saltatory impulse
propagation, one of the best-understood concepts in neurophysiology. However, it took a …

Peripheral nerves are organ-like structures containing diverse cell types to optimize function.
This interactive assembly includes mostly axon-associated Schwann cells, but also …

Understanding nanoparticle–protein interactions is a crucial issue in the development of
targeted nanomaterial delivery. Besides unraveling the composition of the nanoparticle's …

Myelinated nerve fibers are essential for the rapid propagation of action potentials by
saltatory conduction. They form as the result of reciprocal interactions between axons and …

Wallerian degeneration (WD) is considered an essential preparatory stage to the process of
axonal regeneration. In the peripheral nervous system, infiltrating monocyte-derived …

A protein undergoes many types of posttranslation modification. Citrullination is one of these
modifications, where an arginine amino acid is converted to a citrulline amino acid. This …

Abstract Purpose: Perineural invasion (PNI), a common occurrence in oral squamous cell
carcinomas, is associated with poor survival. Consequently, these tumors are treated …

Glial cells and neurons are engaged in a continuous and highly regulated bidirectional
dialog. A remarkable example is the control of myelination. Oligodendrocytes in the central …

The largest pool of free cholesterol in mammals resides in myelin membranes. Myelin
facilitates rapid saltatory impulse propagation by electrical insulation of axons. This function …