N-methyl-D-aspartate receptor (NMDAR) hypofunction in parvalbumin-expressing (PV+)
inhibitory neurons (INs) may contribute to symptoms in patients with schizophrenia (SZ). This …

The drug ketamine has been extensively studied due to its use in anaesthesia, as a model of
psychosis and, most recently, its antidepressant properties. Understanding the physiology of …

Hypofunctioning of the N-methyl-D-aspartate receptor (NMDA-R) has been prominently
implicated in the pathophysiology of schizophrenia (ScZ). The current study tested the …

The profound changes in perception and cognition induced by psychedelic drugs are
thought to act on several levels, including increased glutamatergic activity, altered functional …

Distinct frequency bands can be differentiated from neuronal ensemble recordings, such as
local field potentials or electrocorticogram recordings. Recent years have witnessed a rapid …

Subanesthetic doses of the psychomimetic, ketamine, have been used for many years to
elicit behavioral effects reminiscent of schizophrenia in both healthy humans and in animal …

Despite decades of research, the neural circuit abnormalities underlying schizophrenia
remain elusive. Although studies on schizophrenia patients have yielded important insights …

There is growing evidence that impaired sensory processing significantly contributes to
cognitive deficits found in schizophrenia. Electroencephalography (EEG) has become an …

Cortico-basal ganglia circuits are thought to play a crucial role in the selection and control of
motor behaviors and have also been implicated in the processing of motivational content …

Background NMDAr antagonists induce disturbances to gamma frequency oscillations,
including increasing ongoing gamma activity and reducing evoked gamma oscillations. We …