With the rapid development of biotechnology, the number of biological sequences has
grown exponentially. The continuous expansion of biological sequence data promotes the …

BACKGROUND With increasing significance of developmental programming effects
associated with placental dysfunction, more investigations are devoted to improving the …

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global
pandemic of coronavirus disease 2019 (COVID-19) since December 2019 that has led to …

Single-cell RNA sequencing (scRNA-seq) is a revolutionary breakthrough that determines
the precise gene expressions on individual cells and deciphers cell heterogeneity and …

Background Breast cancer is the most prevalent malignancy in women. Advanced breast
cancer can develop distant metastases, posing a severe threat to the life of patients …

Autoimmunity refers to the phenomenon that the body's immune system produces antibodies
or sensitized lymphocytes to its own tissues to cause an immune response. Immune …

Single-cell RNA sequencing (scRNA-seq) has enabled us to study biological questions at
the single-cell level. Currently, many analysis tools are available to better utilize these …

In recent years, the application of single-cell transcriptomics and spatial transcriptomics
analysis techniques has become increasingly widespread. Whether dealing with single-cell …

Background T cells are present in all stages of tumor formation and play an important role in
the tumor microenvironment. We aimed to explore the expression profile of T cell marker …

Recent advances of single-cell transcriptomics technologies and allied computational
methodologies have revolutionized molecular cell biology. Meanwhile, pioneering …