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Epigenetic-sensitive pathways in personalized therapy of major cardiovascular diseases
The complex pathobiology underlying cardiovascular diseases (CVDs) has yet to be
explained. Aberrant epigenetic changes may result from alterations in enzymatic activities …
explained. Aberrant epigenetic changes may result from alterations in enzymatic activities …
MicroRNAs as diagnostic and prognostic biomarkers in ischemic stroke—a comprehensive review and bioinformatic analysis
Stroke is the second-most common cause of death worldwide. The pathophysiology of
ischemic stroke (IS) is related to inflammation, atherosclerosis, blood coagulation, and …
ischemic stroke (IS) is related to inflammation, atherosclerosis, blood coagulation, and …
Mesenchymal stem cell-derived extracellular vesicle-based therapies protect against coupled degeneration of the central nervous and vascular systems in stroke
Stem cell-based treatments have been suggested as promising candidates for stroke.
Recently, mesenchymal stem cells (MSCs) have been reported as potential therapeutics for …
Recently, mesenchymal stem cells (MSCs) have been reported as potential therapeutics for …
[HTML][HTML] Rho/ROCK pathway and noncoding RNAs: implications in ischemic stroke and spinal cord injury
T Kimura, Y Horikoshi, C Kuriyagawa… - International journal of …, 2021 - mdpi.com
Ischemic strokes (IS) and spinal cord injuries (SCI) are major causes of disability. RhoA is a
small GTPase protein that activates a downstream effector, ROCK. The up-regulation of the …
small GTPase protein that activates a downstream effector, ROCK. The up-regulation of the …
Increased serum exosomal miR-134 expression in the acute ischemic stroke patients
J Zhou, L Chen, B Chen, S Huang, C Zeng, H Wu… - BMC neurology, 2018 - Springer
Background The exosomal miRNAs have been emerged as biomarkers and therapeutic
targets for various diseases, however, the function of exosomal miRNAs in stroke remains …
targets for various diseases, however, the function of exosomal miRNAs in stroke remains …
Gold nanoparticle couples with entropy-driven toehold-mediated DNA strand displacement reaction on magnetic beads: toward ultrasensitive energy-transfer-based …
N Zhang, XM Shi, HQ Guo, XZ Zhao, WW Zhao… - Analytical …, 2018 - ACS Publications
Highly stable circulating microRNAs (miRNAs) are currently recognized as a novel potential
biomarker for clinical cancer diagnosis in the early stage. However, limited by its low …
biomarker for clinical cancer diagnosis in the early stage. However, limited by its low …
miR-137 prevents inflammatory response, oxidative stress, neuronal injury and cognitive impairment via blockade of Src-mediated MAPK signaling pathway in …
R Tian, B Wu, C Fu, K Guo - Aging (Albany NY), 2020 - pmc.ncbi.nlm.nih.gov
Stroke is a leading cause of death and disability worldwide. The purpose of this study was to
investigate the possible role of the microRNA (miRNA or miR) miR-137 in ischemic stroke …
investigate the possible role of the microRNA (miRNA or miR) miR-137 in ischemic stroke …
Elevation of brain-enriched miRNAs in cerebrospinal fluid of patients with acute ischemic stroke
SS Sørensen, AB Nygaard, AL Carlsen… - Biomarker …, 2017 - Springer
Background The purpose of this study was to investigate the potential of cerebrospinal fluid
miRNAs as diagnostic biomarkers of acute ischemic stroke using three different profiling …
miRNAs as diagnostic biomarkers of acute ischemic stroke using three different profiling …
Differential long noncoding RNA expressions in peripheral blood mononuclear cells for detection of acute ischemic stroke
QW Deng, S Li, H Wang, HL Sun, L Zuo, ZT Gu… - Clinical …, 2018 - portlandpress.com
Long noncoding RNAs (lncRNAs) have been highlighted to be involved in the pathological
process of ischemic stroke (IS). The purpose of the present study was to investigate the …
process of ischemic stroke (IS). The purpose of the present study was to investigate the …
[HTML][HTML] Upregulation of miR-874-3p decreases cerebral ischemia/reperfusion injury by directly targeting BMF and BCL2L13
D Jiang, X Sun, S Wang, H Man - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Ischemic stroke represents a major cause of adult physical disability, which is triggered by
cerebral artery occlusion induced blood flow blockage. MiR-874-3p has been reported to be …
cerebral artery occlusion induced blood flow blockage. MiR-874-3p has been reported to be …