The antiapoptotic, antioxidant, proliferative, and angiogenic effects of metallothionein (MT)-
I+ II has resulted in increased focus on their role in oncogenesis, tumor progression, therapy …

Cancer is generally recognized as an age-related disease. In fact, incidence and mortality
rates of most human cancers increase consistently with age up to 90 years, but they plateau …

Cancer is a major cause of death worldwide despite significant advances in surgery and
biology. Several recent studies have suggested that there is a close connection between …

A good number of genome-wide association studies (GWAS), including meta-analyses,
reported that single nucleotide polymorphisms (SNPs) of the IL-6 gene are significantly …

In recent years, pro‐oncogenic mechanisms of the tumour microenvironment (ТМЕ) have
been actively discussed. One of the main cytokines of the TМЕ is interleukin‐1 beta (IL‐1β) …

Introduction 3. IL-6-an overview 4. Obesity, inflammation and cancer 4.1. Obesity and
inflammation 4.2. Inflammation and cance 4.3. Obesity and cancer 4.3. 1. Obesity, IL-6 and …

Esophageal cancer is ranked as the sixth most common cause of cancer death worldwide
and has a substantial effect on public health. In contrast to adenocarcinoma arising from …

Abstract Background and Aim Survivin is an upregulated inhibitor of apoptosis protein in
esophageal cancer (EC), and a promoter region polymorphism (− 31G> C) in the survivin …

Abstract Interleukin-6 (IL-6) plays a contributory role in the progression and severity of many
forms of cancer; it however remains unclear whether the relevance between circulating IL-6 …

Many molecular epidemiologic studies have shown that interleukin-6 (IL-6) polymorphisms
are significantly associated with susceptibility for various cancers. However, the conclusions …