Simple Summary CA125 has been the most promising biomarker for screening ovarian
cancer; however, it still does not have an acceptable accuracy in population-based …

After it was discovered approximately 40 years ago, carbohydrate antigen 125 (CA125)
became the most widely used and concerning biomarker in ovarian cancer screening …

Background Ovarian cancer continues to have a poor prognosis with the majority of women
diagnosed with advanced disease. Therefore, we undertook the UK Collaborative Trial of …

Ovarian cancer is not a single disease and can be subdivided into at least five different
histological subtypes that have different identifiable risk factors, cells of origin, molecular …

Importance Ovarian cancer is relatively rare but the fifth-leading cause of cancer mortality
among United States women. Objective To systematically review evidence on benefits and …

Background Ovarian cancer has a poor prognosis, with just 40% of patients surviving 5
years. We designed this trial to establish the effect of early detection by screening on ovarian …

Epithelial ovarian cancer is the commonest cause of gynaecological cancer-associated
death. The disease typically presents in postmenopausal women, with a few months of …

Context Screening for ovarian cancer with cancer antigen 125 (CA-125) and transvaginal
ultrasound has an unknown effect on mortality. Objective To evaluate the effect of screening …

Importance With approximately 14 000 deaths per year, ovarian cancer is the fifth most
common cause of cancer death among US women and the leading cause of death from …

Background New technologies for the detection of early-stage ovarian cancer are urgently
needed. Pathological changes within an organ might be reflected in proteomic patterns in …