Bioactive sphingolipids as emerging targets for signal transduction in cancer development

W Jia, J Yuan, J Zhang, S Li, W Lin, B Cheng - Biochimica et Biophysica …, 2024 - Elsevier
Sphingolipids, crucial components of cellular membranes, play a vital role in maintaining
cellular structure and signaling integrity. Disruptions in sphingolipid metabolism are …

Piezo1 Is Required for Myoblast Migration and Involves Polarized Clustering in Association with Cholesterol and GM1 Ganglioside

J Vanderroost, T Parpaite, N Avalosse, P Henriet… - Cells, 2023 - mdpi.com
A specific plasma membrane distribution of the mechanosensitive ion channel Piezo1 is
required for cell migration, but the mechanism remains elusive. Here, we addressed this …

Piezo1 Regulation Involves Lipid Domains and the Cytoskeleton and Is Favored by the Stomatocyte–Discocyte–Echinocyte Transformation

A Stommen, M Ghodsi, AS Cloos, L Conrard… - Biomolecules, 2023 - mdpi.com
Piezo1 is a mechanosensitive ion channel required for various biological processes, but its
regulation remains poorly understood. Here, we used erythrocytes to address this question …

Enhanced NK cell proliferation by stress-induced feeder cells

D Lee, M Song, S Kwon - 2024 - researchsquare.com
Natural Killer (NK) cells, integral to the innate immune system, are notable in cell therapies
because for their applicability in allogeneic treatments, distinguishing them from T cells …