Cytokines in CAR T cell–associated neurotoxicity
Chimeric antigen receptor (CAR) T cells provide new therapeutic options for patients with
relapsed/refractory hematologic malignancies. However, neurotoxicity is a frequent, and …
relapsed/refractory hematologic malignancies. However, neurotoxicity is a frequent, and …
Cytokines and chemokines in cerebral malaria pathogenesis
Cerebral malaria is among the major causes of malaria-associated mortality and effective
adjunctive therapeutic strategies are currently lacking. Central pathophysiological processes …
adjunctive therapeutic strategies are currently lacking. Central pathophysiological processes …
The impact of delayed treatment of uncomplicated P. falciparum malaria on progression to severe malaria: A systematic review and a pooled multicentre individual …
Background Delay in receiving treatment for uncomplicated malaria (UM) is often reported to
increase the risk of develo** severe malaria (SM), but access to treatment remains low in …
increase the risk of develo** severe malaria (SM), but access to treatment remains low in …
Pathogenesis of cerebral malaria—inflammation and cytoadherence
J Storm, AG Craig - Frontiers in cellular and infection microbiology, 2014 - frontiersin.org
Despite decades of research on cerebral malaria (CM) there is still a paucity of knowledge
about what actual causes CM and why certain people develop it. Although sequestration of …
about what actual causes CM and why certain people develop it. Although sequestration of …
Erythrocytic ferroportin reduces intracellular iron accumulation, hemolysis, and malaria risk
Malaria parasites invade red blood cells (RBCs), consume copious amounts of hemoglobin,
and severely disrupt iron regulation in humans. Anemia often accompanies malaria disease; …
and severely disrupt iron regulation in humans. Anemia often accompanies malaria disease; …
The anaemia of Plasmodium vivax malaria
Plasmodium vivax threatens nearly half the world's population and is a significant
impediment to achievement of the millennium development goals. It is an important, but …
impediment to achievement of the millennium development goals. It is an important, but …
Prevalence and risk factors associated with asymptomatic malaria among school children: repeated cross-sectional surveys of school children in two ecological zones …
Abstract Background Asymptomatic Plasmodium infections significantly drive malaria
transmission and impact control and elimination strategies, but are largely uncharacterized …
transmission and impact control and elimination strategies, but are largely uncharacterized …
The striking mimics between COVID-19 and malaria: A review
EHE Konozy, MEM Osman… - Frontiers in …, 2022 - frontiersin.org
Objectives COVID-19 is a transmissible illness triggered by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). Since its onset in late 2019 in Wuhan city of China …
syndrome coronavirus 2 (SARS-CoV-2). Since its onset in late 2019 in Wuhan city of China …
Tumour necrosis factor-α as a prognostic biomarker of severe malaria: a systematic review and meta-analysis
Background Tumour necrosis factor-alpha (TNF-α) levels are reportedly altered during
malaria. In this systematic review and meta-analysis, we aimed to collect and compare data …
malaria. In this systematic review and meta-analysis, we aimed to collect and compare data …
Characterisation of the opposing effects of G6PD deficiency on cerebral malaria and severe malarial anaemia
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is believed to confer protection
against Plasmodium falciparum malaria, but the precise nature of the protective effect has …
against Plasmodium falciparum malaria, but the precise nature of the protective effect has …