Sugar-sweetened beverages (SSBs) are a major source of added sugars in the diet. A
robust body of evidence has linked habitual intake of SSBs with weight gain and a higher …

Currently, obesity has become a global health issue and is referred to as an epidemic.
Dysfunctional obese adipose tissue plays a pivotal role in the development of insulin …

Preclinical and clinical data suggest that fibroblast growth factor 21 (FGF21) is anti-fibrotic,
improves metabolic status and has potential to treat non-alcoholic steatohepatitis (NASH) …

Excessive sugar consumption is increasingly considered as a contributor to the emerging
epidemics of obesity and the associated cardiometabolic disease. Sugar is added to the diet …

There has been a rise in the prevalence of nonalcoholic fatty liver disease (NAFLD),
paralleling a worldwide increase in diabetes and metabolic syndrome. NAFLD, a continuum …

Non-alcoholic fatty liver disease (NAFLD) and chronic kidney disease (CKD) are worldwide
public health problems, affecting up to 25–30%(NAFLD), and up to 10–15%(CKD) of the …

During the last century, there has been an increasing prevalence of hyperuricaemia noted in
many populations. While uric acid is usually discussed in the context of gout …

Nonalcoholic fatty liver disease (NAFLD) is a main hepatic manifestation of metabolic
syndrome. It represents a wide spectrum of histopathological abnormalities ranging from …

Xanthine oxidoreductase (XOR) consists of two different forms, xanthine dehydrogenase
and xanthine oxidase (XO), and is a rate-limiting enzyme of uric acid production from …

Sugar-sweetened beverages (SSBs) have little nutritional value and a robust body of
evidence has linked the intake of SSBs to weight gain and risk of type 2 diabetes (T2D) …