Evidence-based guideline for the diagnosis and management of eosinophilic granulomatosis with polyangiitis
Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare anti-neutrophil cytoplasmic
antibody (ANCA)-associated vasculitis, characterized by asthma, eosinophilia and …
antibody (ANCA)-associated vasculitis, characterized by asthma, eosinophilia and …
ANCA-associated vasculitis
The anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAVs) are a
group of disorders involving severe, systemic, small-vessel vasculitis and are characterized …
group of disorders involving severe, systemic, small-vessel vasculitis and are characterized …
Diagnosis and management of ANCA-associated vasculitis
Antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis consists of two main
diseases, granulomatosis with polyangiitis and microscopic polyangiitis, and remains …
diseases, granulomatosis with polyangiitis and microscopic polyangiitis, and remains …
Genetic map** across autoimmune diseases reveals shared associations and mechanisms
MR Lincoln, N Connally, PP Axisa, C Gasperi… - Nature …, 2024 - nature.com
Autoimmune and inflammatory diseases are polygenic disorders of the immune system.
Many genomic loci harbor risk alleles for several diseases, but the limited resolution of …
Many genomic loci harbor risk alleles for several diseases, but the limited resolution of …
EULAR recommendations for the management of ANCA-associated vasculitis: 2022 update
B Hellmich, B Sanchez-Alamo, JH Schirmer… - Annals of the rheumatic …, 2024 - Elsevier
Background Since the publication of the EULAR recommendations for the management of
antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in 2016, several …
antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) in 2016, several …
Mepolizumab for eosinophilic granulomatosis with polyangiitis: a European multicenter observational study
Objective Mepolizumab proved to be an efficacious treatment for eosinophilic
granulomatosis with polyangiitis (EGPA) at a dose of 300 mg every 4 weeks in the …
granulomatosis with polyangiitis (EGPA) at a dose of 300 mg every 4 weeks in the …
Genetics of ANCA-associated vasculitis: role in pathogenesis, classification and management
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) comprises
granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA) and eosinophilic …
granulomatosis with polyangiitis (GPA), microscopic polyangiitis (MPA) and eosinophilic …
Genoty** and population characteristics of the China Kadoorie Biobank
RG Walters, IY Millwood, K Lin, DS Valle, P McDonnell… - Cell genomics, 2023 - cell.com
Summary The China Kadoorie Biobank (CKB) is a population-based prospective cohort of>
512,000 adults recruited from 2004 to 2008 from 10 geographically diverse regions across …
512,000 adults recruited from 2004 to 2008 from 10 geographically diverse regions across …
Eosinophil knockout humans: uncovering the role of eosinophils through eosinophil-directed biological therapies
The enigmatic eosinophil has emerged as an exciting component of the immune system,
involved in a plethora of homeostatic and inflammatory responses. Substantial progress has …
involved in a plethora of homeostatic and inflammatory responses. Substantial progress has …
Eosinophilia Induced by Blocking the IL-4/IL-13 Pathway: Potential Mechanisms and Clinical Outcomes.
Five biological drugs are currently marketed for treatment of uncontrolled severe asthma.
They all block type 2 inflammatory pathways by targeting IgE (omalizumab), the IL-5 …
They all block type 2 inflammatory pathways by targeting IgE (omalizumab), the IL-5 …