Alzheimer's disease (AD) is an age-related disease pathologically defined by the deposition
of amyloid plaques and neurofibrillary tangles in the brain parenchyma. Single-cell profiling …

Ageing is a crucial risk factor for Alzheimer's disease (AD) and is characterised by systemic
changes in both intracellular and extracellular microenvironments that affect the entire body …

Astrocytes are a large and diverse population of morphologically complex cells that exist
throughout nervous systems of multiple species. Progress over the last two decades has …

To uncover molecular changes underlying blood-brain-barrier dysfunction in Alzheimer's
disease, we performed single nucleus RNA sequencing in 24 Alzheimer's disease and …

The neuroscience community has witnessed a tremendous expansion of glia research. Glial
cells are now on center stage with leading roles in the development, maturation, and …

Alzheimer's disease (AD) is the most common form of dementia, characterized by
progressive cognitive impairment and neurodegeneration. Extensive clinical and genomic …

Macroglia fulfill essential functions in the adult vertebrate brain, producing and maintaining
neurons and regulating neuronal communication. However, we still know little about their …

Chicken lung is an important target organ of avian influenza virus (AIV) infection, and
different pathogenic virus strains lead to opposite prognosis. Using a single-cell RNA …