A review of the antiviral activities of glycyrrhizic acid, glycyrrhetinic acid and glycyrrhetinic acid monoglucuronide

J Zuo, T Meng, Y Wang, W Tang - Pharmaceuticals, 2023 - mdpi.com
Licorice, a natural medicine derived from the roots and rhizomes of Glycyrrhiza species,
possesses a wide range of therapeutic applications, including antiviral properties …

The impact of mucormycosis (black fungus) on SARS-CoV-2-infected patients: at a glance

MR Islam, MM Rahman, MT Ahasan, N Sarkar… - … Science and Pollution …, 2022 - Springer
The emergence of various diseases during the COVID-19 pandemic made health workers
more attentive, and one of the new pathogens is the black fungus (mucormycosis). As a …

Redox homeostasis alteration is restored through melatonin treatment in COVID-19 patients: A preliminary study

ME Soto, I Pérez-Torres, L Manzano-Pech… - International Journal of …, 2024 - mdpi.com
Type II pneumocytes are the target of the SARS-CoV-2 virus, which alters their redox
homeostasis to increase reactive oxygen species (ROS). Melatonin (MT) has antioxidant …

Designing an Efficient Biocatalyst for the Phosphoribosylation of Antiviral Pyrazine-2-carboxamide Derivatives

EA Zayats, IV Fateev, YA Abramchik… - ACS …, 2024 - ACS Publications
The development of technologies for the efficient synthesis of innovative antiviral
compounds remains an important challenge for modern biotechnology, especially in the …

Phytochemicals of Withania somnifera as a Future Promising Drug against SARS-CoV-2: Pharmacological Role, Molecular Mechanism, Molecular Docking …

S Ramli, YS Wu, K Batumalaie, RM Guad, KW Choy… - Microorganisms, 2023 - mdpi.com
Coronavirus disease (COVID-19) has killed millions of people since first reported in Wuhan,
China, in December 2019. Intriguingly, Withania somnifera (WS) has shown promising …

Favipiravir attachment to a conical nanocarbon: DFT assessments of the drug delivery approach

K Harismah, SA Shahrtash, AR Arabi, R Khadivi… - Computational and …, 2022 - Elsevier
Density functional theory (DFT) quantum calculations were performed to investigate
attachment of favipiravir (FAV) to a conical nanocarbon (FCN) for assessments of the drug …

N-acetyl cysteine restores the diminished activity of the antioxidant enzymatic system caused by SARS-CoV-2 infection: Preliminary findings

ME Soto, L Manzano-Pech, A Palacios-Chavarría… - Pharmaceuticals, 2023 - mdpi.com
SARS-CoV-2 infects type II pneumocytes and disrupts redox homeostasis by overproducing
reactive oxygen species (ROS). N-acetyl cysteine (NAC) is a precursor of the synthesis of …

[HTML][HTML] Transient SARS-CoV-2 RNA-dependent RNA polymerase mutations after remdesivir treatment for chronic COVID-19 in two transplant recipients: case report …

S Yang, A Multani, JM Garrigues, MS Oh, P Hemarajata… - Microorganisms, 2023 - mdpi.com
Remdesivir is the first FDA-approved drug for treating severe SARS-CoV-2 infection and
targets RNA-dependent RNA polymerase (RdRp) that is required for viral replication. To …

Impact of alteplase on mortality in critically ill patients with COVID-19 and pulmonary embolism

OV Oliynyk, M Rorat, SO Solyarik, VA Lukianchuk… - Viruses, 2023 - mdpi.com
COVID-19 is an independent risk factor for pulmonary embolism (PE). Little is known about
alteplase therapy in this patient group. A retrospective study analyzed 74 patients with PE …

Mortality, intensive care unit admission, and intubation among hospitalized patients with COVID-19: a one-year retrospective study in Jordan

K Al Oweidat, R Al-Amer, MY Saleh… - Journal of Clinical …, 2023 - mdpi.com
COVID-19 is a public health crisis that has caused numerous deaths, necessitated an
increased number of hospital admissions, and led to extended inpatient stays. This study …