Neuroinflammation mechanisms of neuromodulation therapies for anxiety and depression

B Guo, M Zhang, W Hao, Y Wang, T Zhang… - Translational …, 2023 - nature.com
Mood disorders are associated with elevated inflammation, and the reduction of symptoms
after multiple treatments is often accompanied by pro-inflammation restoration. A variety of …

Emotion, motivation, decision-making, the orbitofrontal cortex, anterior cingulate cortex, and the amygdala

ET Rolls - Brain Structure and Function, 2023 - Springer
The orbitofrontal cortex and amygdala are involved in emotion and in motivation, but the
relationship between these functions performed by these brain structures is not clear. To …

Frontostriatal salience network expansion in individuals in depression

CJ Lynch, IG Elbau, T Ng, A Ayaz, S Zhu, D Wolk… - Nature, 2024 - nature.com
Decades of neuroimaging studies have shown modest differences in brain structure and
connectivity in depression, hindering mechanistic insights or the identification of risk factors …

The prefrontal cortex, pathological anxiety, and anxiety disorders

MM Kenwood, NH Kalin, H Barbas - Neuropsychopharmacology, 2022 - nature.com
Anxiety is experienced in response to threats that are distal or uncertain, involving changes
in one's subjective state, autonomic responses, and behavior. Defensive and physiologic …

Schizophrenia: from neurochemistry to circuits, symptoms and treatments

OD Howes, BR Bukala, K Beck - Nature Reviews Neurology, 2024 - nature.com
Schizophrenia is a leading cause of global disability. Current pharmacotherapy for the
disease predominantly uses one mechanism—dopamine D2 receptor blockade—but often …

Topographic organization of the human subcortex unveiled with functional connectivity gradients

Y Tian, DS Margulies, M Breakspear, A Zalesky - Nature neuroscience, 2020 - nature.com
Brain atlases are fundamental to understanding the topographic organization of the human
brain, yet many contemporary human atlases cover only the cerebral cortex, leaving the …

Printed synaptic transistor–based electronic skin for robots to feel and learn

F Liu, S Deswal, A Christou, M Shojaei Baghini… - Science Robotics, 2022 - science.org
An electronic skin (e-skin) for the next generation of robots is expected to have biological
skin-like multimodal sensing, signal encoding, and preprocessing. To this end, it is …

The self in context: brain systems linking mental and physical health

L Koban, PJ Gianaros, H Kober… - Nature Reviews …, 2021 - nature.com
Increasing evidence suggests that mental health and physical health are linked by neural
systems that jointly regulate somatic physiology and high-level cognition. Key systems …

[HTML][HTML] Schizophrenia, dopamine and the striatum: from biology to symptoms

RA McCutcheon, A Abi-Dargham, OD Howes - Trends in neurosciences, 2019 - cell.com
The mesolimbic hypothesis has been a central dogma of schizophrenia for decades,
positing that aberrant functioning of midbrain dopamine projections to limbic regions causes …

[HTML][HTML] The influences of emotion on learning and memory

CM Tyng, HU Amin, MNM Saad, AS Malik - Frontiers in psychology, 2017 - frontiersin.org
Emotion has a substantial influence on the cognitive processes in humans, including
perception, attention, learning, memory, reasoning, and problem solving. Emotion has a …