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[HTML][HTML] Cell-penetrating peptide-based delivery of macromolecular drugs: development, strategies, and progress
Z Sun, J Huang, Z Fishelson, C Wang, S Zhang - Biomedicines, 2023 - mdpi.com
Cell-penetrating peptides (CPPs), developed for more than 30 years, are still being
extensively studied due to their excellent delivery performance. Compared with other …
extensively studied due to their excellent delivery performance. Compared with other …
Challenge to overcome current limitations of cell-penetrating peptides
The penetration of biological membranes is a prime obstacle for the delivery of
pharmaceutical drugs. Cell-penetrating peptide (CPP) is an efficient vehicle that can deliver …
pharmaceutical drugs. Cell-penetrating peptide (CPP) is an efficient vehicle that can deliver …
Bioinspired Tumor‐Targeting and Biomarker‐Activatable Cell‐Material Interfacing System Enhances Osteosarcoma Treatment via Biomineralization
Osteosarcoma is an aggressive malignant tumor that primarily develops in children and
adolescents. The conventional treatments for osteosarcoma often exert negative effects on …
adolescents. The conventional treatments for osteosarcoma often exert negative effects on …
Tumor microenvironment-responsive cell-penetrating peptides: design principle and precision delivery
C Wang, B Wang, Q Zhang, S Zhang - Colloids and Surfaces B …, 2024 - Elsevier
Cell-penetrating peptides (CPPs) are promising vehicles for intracellular delivery of different
cargoes. Although various CPPs are designed for targeted delivery of nanomedicines and …
cargoes. Although various CPPs are designed for targeted delivery of nanomedicines and …
Activatable cell-penetrating peptides: 15 years of research
H de Jong, KM Bonger, DWPM Löwik - RSC chemical biology, 2020 - pubs.rsc.org
An important hurdle for the intracellular delivery of large cargo is the cellular membrane,
which protects the cell from exogenous substances. Cell-penetrating peptides (CPPs) can …
which protects the cell from exogenous substances. Cell-penetrating peptides (CPPs) can …
Photoactive nanocarriers for controlled delivery
Q **ong, Y Lim, D Li, K Pu, L Liang… - Advanced Functional …, 2020 - Wiley Online Library
Photoactive nanocarriers have emerged as robust and minimally invasive systems for the on‐
demand delivery of active payloads. The easy manipulation offered by light irradiation as an …
demand delivery of active payloads. The easy manipulation offered by light irradiation as an …
Two-Photon Sensitive Coumarinyl Photoremovable Protecting Groups with Rigid Electron-Rich Cycles Obtained by Domino Reactions Initiated by a 5-exo-Dig …
J Chaud, C Morville, F Bolze, D Garnier… - Organic …, 2021 - ACS Publications
We herein report the design, synthesis, and photophysical characterization of extended and
rigid coumarinyl derivatives showing large two-photon sensitivities (δaΦu≤ 125 GM) at 740 …
rigid coumarinyl derivatives showing large two-photon sensitivities (δaΦu≤ 125 GM) at 740 …
[HTML][HTML] Design, synthesis, and utility of defined molecular scaffolds
A growing theme in chemistry is the joining of multiple organic molecular building blocks to
create functional molecules. Diverse derivatizable structures—here termed “scaffolds” …
create functional molecules. Diverse derivatizable structures—here termed “scaffolds” …
Cell-penetrating peptide-mediated biomolecule transportation in artificial lipid vesicles and living cells
A Miwa, K Kamiya - Molecules, 2024 - pmc.ncbi.nlm.nih.gov
Signal transduction and homeostasis are regulated by complex protein interactions in the
intracellular environment. Therefore, the transportation of impermeable macromolecules …
intracellular environment. Therefore, the transportation of impermeable macromolecules …
Advances in cell penetrating peptides and their functionalization of polymeric nanoplatforms for drug delivery
Y Tian, S Zhou - Wiley Interdisciplinary Reviews: Nanomedicine …, 2021 - Wiley Online Library
Cell penetrating peptides (CPPs), known as protein translocation domains, have emerged
as efficient molecular transporters to overcome biological barriers and deliver cell …
as efficient molecular transporters to overcome biological barriers and deliver cell …