Bidirectional crosstalk along the gut-liver axis controls gastrointestinal health and disease
and exploits environmental and host mediators. Nutrients, microbial antigens, metabolites …

The gut and the liver are characterized by mutual interactions between both organs, the
microbiome, diet and other environmental factors. The sum of these interactions is …

Primary sclerosing cholangitis (PSC) offers unique opportunities to explore the gut–liver axis
owing to the close association between liver disease and colonic inflammation. It is well …

Objective Conflicting microbiota data exist for primary sclerosing cholangitis (PSC) and
experimental models. Goal: define the function of complex resident microbes and their …

Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease characterized by
chronic inflammation and progressive fibrosis of the biliary tree. The majority of PSC patients …

Primary sclerosing cholangitis (PSC) was declared one of the biggest unmet needs in
hepatology during International Liver Congress 2016 in Berlin. Since then, not much has …

Exposure to multiple substances is a challenge for risk evaluation. Currently, there is an
ongoing debate if generic “mixture assessment/allocation factors”(MAF) should be …

Timely liver function recovery (LFR) is crucial for postoperative hepatocellular carcinoma
(HCC) patients. Here, we established the significance of LFR on patient long-term survival …

While fecal microbiota transplantation (FMT) shows promise in treating human diseases,
oral capsule FMT is more accepted and accessible to patients. However, microbe selection …

Background Cholestatic liver diseases (CLD) comprise a variety of disorders of bile
formation, which causes chronic exposure to bile acid (BA) in the liver generally and results …