Antimicrobial peptides grafted onto the surface of N-acetylcysteine-chitosan nanoparticles can revitalize drugs against clinical isolates of Mycobacterium tuberculosis

LMDG Primo, CA Roque-Borda, CSC Canales… - Carbohydrate …, 2024 - Elsevier
Tuberculosis is caused by Mycobacterium tuberculosis (MTB) and is the leading cause of
death from infectious diseases in the World. The search for new antituberculosis drugs is a …

Real-time label-free detection of dynamic aptamer–small molecule interactions using a nanopore nucleic acid conformational sensor

RG Chingarande, K Tian, Y Kuang, A Sarangee… - Proceedings of the …, 2023 - pnas.org
Nucleic acids can undergo conformational changes upon binding small molecules. These
conformational changes can be exploited to develop new therapeutic strategies through …

Screening of natural compounds that targets glutamate racemase of Mycobacterium tuberculosis reveals the anti-tubercular potential of flavonoids

A Pawar, P Jha, M Chopra, U Chaudhry, D Saluja - Scientific reports, 2020 - nature.com
Tuberculosis (TB) is caused by Mycobacterium tuberculosis (MTB), a highly infectious
disease accounting for nearly 1.5 million deaths every year and has been a major global …

Saúde Pública: bases conceituais

AA Rocha, CLG Cesar - Saúde pública: bases conceituais, 2008 - pesquisa.bvsalud.org
Localização: BR67. 1; 614, 347. DE (DESTOMBADO EX. 1). 49814/2008/BR67. 1; 614, 347,
ex. 2. DE. 49890/2008/BR67. 1; 614, 347, ex. 3. DE. 49891/2008/BR67. 1; 614, 347, ex. 4 …

Methylotrophy in mycobacteria: dissection of the methanol metabolism pathway in Mycobacterium smegmatis

AA Dubey, SR Wani, V Jain - Journal of Bacteriology, 2018 - journals.asm.org
The mycobacteria comprise both pathogenic and nonpathogenic bacteria. Although several
features related to pathogenicity in various mycobacterial species, such as Mycobacterium …

Cloning, expression, purification, and characterization of glutamate decarboxylase (Rv3432c) from Mycobacterium tuberculosis

R Rai, R Paroha, S Rai, AK Singh, R Chaurasia… - International …, 2025 - Springer
Glutamate decarboxylase (Gad), a pyridoxal 5′-phosphate (PLP)-dependent enzyme,
catalyzes the conversion of glutamate to γ-aminobutyric acid (GABA), consuming a proton in …

[HTML][HTML] On-Chip Isoniazid Exposure of Mycobacterium smegmatis Penicillin-Binding Protein (PBP) Mutant Using Time-Lapse Fluorescent Microscopy

M Elitas - Micromachines, 2018 - mdpi.com
Antibiotic resistance has been one of the biggest threats to global health. Despite the
available prevention and control strategies and efforts in develo** new antibiotics, the …

[HTML][HTML] Rupal Rai 1 Ruchi Paroha 2 Sandesh Rai 3 Anirudh K. Singh 4

R Chaurasia, N Agarwal, MK Pandey - assets-eu.researchsquare.com
Glutamate decarboxylase (Gad), a pyridoxal 5'-phosphate (PLP)-dependent enzyme,
catalyses the conversion of glutamate to γ-aminobutyric acid (GABA), consuming a proton in …