Nature embeds some of its molecular machinery, including ion pumps, within lipid bilayer
membranes. This has inspired chemists to attempt to develop synthetic analogues to exploit …

The click concept, as originally discussed by Sharpless, Finn, and Kolb, is both powerful and
simple. Kolb et al. suggested that in the search for functional molecules, chemists should …

Abstract 'Impossible'rotaxanes, which are constituted by interlocked components without
obvious binding motifs, have attracted the interest of the mechanically interlocked molecules …

Sacrificial chemical bonds have been used effectively to increase the toughness of
elastomers because such bonds dissociate at forces significantly below the fracture limit of …

Poly [n] catenanes have exceptional mechanical bonding properties that give them
tremendous potential for use in the development of molecular machines and soft materials …

Abstract The use of 2, 5‐diformylpyrrole in self‐assembly reactions with diamines and Zn
(II)/Cd (II) salts allowed the preparation of [2] catenane, trefoil knot, and Borromean rings …

A doubly-interlocked [2] catenane–or Solomon link–undergoes a complex conformational
change upon addition of sulfate in methanol. This transformation generates a single pocket …

Inspired by interlocked oligonucleotides, peptides and knotted proteins, synthetic systems
where a macrocycle cages a bioactive species that is “switched on” by breaking the …

The chemistry of mechanically interlocked molecules (MIMs) such as catenane and rotaxane
is full of new opportunities for the presence of a mechanical bond, and the efficient synthesis …

Studies of complex systems and emerging properties to mimic biosystems are at the
forefront of chemical research. Dynamic multistep cascades, especially those exhibiting …