[HTML][HTML] Clofazimine: A useful antibiotic for drug-resistant tuberculosis

R Mirnejad, A Asadi, S Khoshnood, H Mirzaei… - Biomedicine & …, 2018 - Elsevier
Drug resistance is still the major threat to global tuberculosis (TB) control, and drug-resistant
(DR) Mycobacterium tuberculosis (M. tuberculosis) strains have become the main challenge …

Pharmacologic management of Mycobacterium ulcerans infection

TS Van Der Werf, YT Barogui, PJ Converse… - Expert review of …, 2020 - Taylor & Francis
ABSTRACT Introduction Pharmacological treatment of Buruli ulcer (Mycobacterium ulcerans
infection; BU) is highly effective, as shown in two randomized trials in Africa. Areas covered …

Uniform multidrug therapy for leprosy patients in Brazil (U-MDT/CT-BR): Results of an open label, randomized and controlled clinical trial, among multibacillary …

GO Penna, S Bührer-Sékula, LRS Kerr… - PLoS neglected …, 2017 - journals.plos.org
Background Leprosy control is based on early diagnosis and multidrug therapy. For
treatment purposes, leprosy patients can be classified as paucibacillary (PB) or …

An enhanced regimen as post-exposure chemoprophylaxis for leprosy: PEP++

LF Mieras, AT Taal, WH Van Brakel, E Cambau… - BMC infectious …, 2018 - Springer
The ongoing transmission of Mycobacterium (M.) leprae reflected in a very slow decline in
leprosy incidence, forces us to be innovative and conduct cutting-edge research. Single …

Treatment of leprosy

DNJ Lockwood, B Kumar - Bmj, 2004 - bmj.com
Leprosy still poses major therapeutic challenges. We have effective antibiotics to cure the
infection, but the immune mediated peripheral nerve damage can continue long after …

Evaluating the effect of clofazimine against Mycobacterium tuberculosis given alone or in combination with pretomanid, bedaquiline or linezolid

S Kim, A Louie, GL Drusano, M Almoslem, S Kim… - International journal of …, 2022 - Elsevier
In recent years, clofazimine (CFZ) has been regaining prominence for the treatment of
tuberculosis. However, it shows limited efficacy as a single drug and optimal combination …

Safer and newer antimicrobial drugs for leprosy–time to test monthly ROM in an adequately powered randomised trial?

DNJ Lockwood, GO Penna, S Lambert, VV Pai… - Leprosy …, 2022 - leprosyreview.org
In the last decade many leprologists around the world have been advocating the
development and testing of new antimicrobial treatments for leprosy but limited new clinical …

Evaluation of agreement between tests for the diagnosis of leprosy

AR Silva, MFA Queiroz, EAY Ishikawa… - Jornal Brasileiro de …, 2017 - SciELO Brasil
Introduction: Leprosy is a chronic infectious disease caused by the intracellular parasite
Mycobacterium leprae. The diagnosis is essentially clinical, based on symptoms, skin exam …

The imperatives of leprosy treatment in the pre‐and post‐global leprosy elimination era: Appraisal of changing the scenario to current status

VN Sehgal, K Sardana, S Dogra - Journal of dermatological …, 2008 - Taylor & Francis
Leprosy was supposed to be eliminated by WHO at the global level by the end of the year
2000; however, it still remains a significant public health problem at a national level in six …

[PDF][PDF] Leprosy in Iran: an analysis of 195 cases from 1994-2009

F Golfurushan, M Sadeghi, M Goldust… - Journal of the Pakistan …, 2011 - researchgate.net
Objectives: To estimate the prevalence of Leprosy in Azerbaijan, Iran. Methods: A total of
195 new leprosy cases referred to and registered in Bababaghi Center, Azerbaijan …