Cardiovascular disease in systemic lupus erythematosus: a comprehensive update

M Giannelou, CP Mavragani - Journal of autoimmunity, 2017 - Elsevier
Heightened rates of both cardiovascular (CV) events and subclinical atherosclerosis,
documented by imaging and vascular function techniques are well established in systemic …

[PDF][PDF] One year in review 2017: systemic lupus erythematosus

GMC La Paglia, MC Leone, G Lepri… - Clin Exp …, 2017 - clinexprheumatol.org
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that predominately
affects women. It is characterised by a broad spectrum of clinical manifestations, however, its …

Endothelial dysfunction in systemic lupus erythematosus and systemic sclerosis: A common trigger for different microvascular diseases

L Moschetti, S Piantoni, E Vizzardi, E Sciatti… - Frontiers in …, 2022 - frontiersin.org
This review describes the complex interplay between inflammation, vasculopathy and
fibrosis that involve the heart and peripheral small vessels, leading to endothelial stiffness …

Novel insights in systemic lupus erythematosus and atherosclerosis

V Teixeira, LS Tam - Frontiers in Medicine, 2018 - frontiersin.org
Introduction The systemic inflammatory nature of systemic lupus erythematosus (SLE) is well
patent not only in the diverse clinical manifestations of the disease but also in the increased …

Lupus nephritis: improving treatment options

M Kostopoulou, S Pitsigavdaki, G Bertsias - Drugs, 2022 - Springer
Despite improvements in patient and renal death rates following the introduction of potent
immunosuppressive drugs in earlier decades, a sizeable fraction of patients with lupus …

Update on cardiovascular disease in lupus

LB Lewandowski, MJ Kaplan - Current opinion in rheumatology, 2016 - journals.lww.com
Recent discoveries have placed increased emphasis on the immunology of atherosclerotic
cardiovascular disease. Understanding the factors that drive the increased risk for …

Evaluation of endothelial function by flow-mediated dilation: a comprehensive review in rheumatic disease

L Moroni, C Selmi, C Angelini, PL Meroni - Archivum immunologiae et …, 2017 - Springer
Flow-mediated dilation (FMD) represents a non-invasive marker of endothelial function to
evaluate vascular homeostasis, which reflects the effects of several mechanisms, including …

Endothelial dysfunction in systemic lupus erythematosus: pathogenesis, assessment and therapeutic opportunities

D Mauro, A Nerviani - Reviews on Recent Clinical Trials, 2018 - ingentaconnect.com
Background: Systemic Lupus Erythematosus (SLE) is characterised by increased mortality
secondary to Cardiovascular Diseases (CVD). Despite being common in SLE, traditional …

Type I Interferon as cardiovascular risk factor in systemic and cutaneous lupus erythematosus: a systematic review

C Kirchler, E Husar-Memmer, K Rappersberger… - Autoimmunity …, 2021 - Elsevier
Objective Patients with systemic lupus erythematosus (SLE) have a high burden of
cardiovascular disease (CVD) of multifactorial origin. The aim of this systematic review is to …

Vascular inflammation and dysfunction in lupus-prone mice-IL-6 as mediator of disease initiation

P Marczynski, M Meineck, N **a, H Li, D Kraus… - International journal of …, 2021 - mdpi.com
Background: Systemic lupus erythematosus (SLE) is a chronic inflammatory autoimmune
disease and patients are under an increased risk for cardiovascular (CV) events and …